ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2024
Association Between the Trajectories of the Atherogenic Index of Plasma and Prediabetes Progression to Diabetes: A Retrospective Cohort Study.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Involvement of C-peptide in the progression of type 2 diabetes mellitus through triglyceride-centered lipid metabolism.Hormones (Athens, Greece) · 2026Article
- Article
- Article
- The correlation between the trajectory of plasma atherosclerosis-inducing index in the examination population and the risk of developing metabolic dysfunction-associated steatotic liver disease.Frontiers in endocrinology · 2026Article
- Association of the atherogenic index of plasma with the risk of cardiovascular disease and death among diabetic or prediabetic adults.Endocrine · 2025Article
- Association Between Cumulative Atherogenic Index of Plasma and New-Onset Stroke Among Middle-Aged and Elderly Chinese Patients With Stages 0-3 Cardiovascular-Kidney-Metabolic Syndrome: A Longitudinal Cohort Study.Brain and behavior · 2025Article
- Association between the atherogenic index of plasma and long-term risk of type 2 diabetes: a 12-year cohort study based on the Japanese population.Cardiovascular diabetology · 2025Article
- Commentary: The atherogenic index of plasma is associated with an increased risk of diabetes in non-obese adults: a cohort study.Frontiers in endocrinology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aims to analyze baseline profiles and longitudinal changes in Atherogenic Index of Plasma (AIP) among individuals with prediabetes to identify distinct AIP trajectories and assess their significance in predicting diabetes onset. Methods: This retrospective cohort study analyzed data from 8346 participants who underwent multiple general health checks. Utilizing latent class trajectory modeling and Cox proportional hazards analyses, it examined the association between the AIP index and health outcomes. Results: Over about 2 years, 2897 people progressed from prediabetes to diabetes. Individuals in the highest quartile of AIP had a higher diabetes risk compared to the lowest quartile (HR = 1.138, 95% CI1.013-1.278). Trajectory analysis revealed three groups: low-stable, moderate-stable, and high-stable, based on AIP index. The moderate-stable group showed a 1.117-fold risk of diabetes progression (95% CI1.026-1.217), while the high-stable group had an elevated risk (HR = 1.224, 95% CI1.059-1.415). Conclusion: The study highlights a clear association between higher AIP index levels at baseline and an increased risk of diabetes progression. It underscores the significance of utilizing the AIP index as a predictive tool to identify those at risk, emphasizing the need for targeted preventive measures in managing diabetes progression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.