Evidence map›Paper›PMID 39660124›Full record

ReviewFrontiers in immunology2024

Traditional Chinese medicine and its components effectively reduce resistance mediated by immune checkpoint inhibitors.

Mingxin Guo, Wentong Fang, Zhiqiang Hu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mingxin GuoDepartment of Pharmacy, The Affiliated Yixing Hospital of Jiangsu University, Yixing, China.
Wentong FangDepartment of pharmacy, Jiangsu Province Hospital, Nanjing, China.
Zhiqiang HuDepartment of Pharmacy, The Affiliated Yixing Hospital of Jiangsu University, Yixing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy has become a global focus in cancer treatment and research, with promising results from targeting immune checkpoints in tumors like non-small cell lung cancer, colon cancer, and melanoma. However, resistance to immune checkpoint inhibitors (ICIs) remains a significant challenge. Traditional Chinese medicine (TCM), known for its low toxicity and minimal side effects, shows promise in enhancing cancer treatment when combined with modern therapies. This study reviews recent research on ICIs resistance mechanisms and highlights TCM's potential in overcoming this resistance, aiming to improve ICIs efficacy while minimizing toxicity.

Indexed as

Drug Resistance, NeoplasmDrugs, Chinese HerbalImmune Checkpoint InhibitorsMedicine, Chinese TraditionalNeoplasmsAnimalsHumansImmunotherapyDrugs, Chinese HerbalImmune Checkpoint InhibitorsChinese herbsdrug resistanceimmune checkpoint inhibitorstraditional Chinese medicinetumor immunotherapy

Identifiers

PMID39660124
PMCPMC11628391

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.