ArticleBrain communications2024
Prevalence of hypothyroidism in older adults and its association with cognition: a cross-sectional study from a South Indian ageing urban cohort.
Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors.
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Abstract
The study conducted on a South Indian urban cohort aimed to emphasize the prevalence and patterns of hypothyroidism and its association with cognition among individuals aged 45 years and above. A cross-sectional design was adopted, utilizing data from the Tata Longitudinal Study of Aging cohort, comprising 1201 non-demented participants in Bangalore, South India. The study contains detailed clinical assessments, including medical history, physical examination and cognitive tests such as the COGNITO battery, Hindi Mental State Examination and Addenbrooke's Cognition Examination III. Biochemical tests were utilized to quantify plasma levels of thyroid-stimulating hormone, triiodothyronine and thyroxine. Participants were categorized based on medication history and thyroid hormone levels. The study findings showed a 17.69% prevalence of hypothyroidism, with 6.22% being classified as overt hypothyroidism and 93.78% as subclinical hypothyroidism. The prevalence was significantly higher in females compared with males (
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