Evidence map›Paper›PMID 39659890›Full record

ReviewInternational journal of endocrinology2024

Interference Mechanisms of Endocrine System and Other Systems of Endocrine-Disrupting Chemicals in Cosmetics-In Vitro Studies.

Yixuan Zhang, Lihong Tu, Jian Chen, Lihong Zhou

Abstract readReview
In one paragraph

Review in International journal of endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yixuan ZhangNMPA Key Laboratory for Monitoring and Evaluation of Cosmetics, Shanghai Innovation R&D, Testing and Evaluation Technical Service Platform of Cosmetics (22DZ2292100), Department of Evaluation of Cosmetics, Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan Rd. W., Changning, Shanghai 200336, China.ORCID https://orcid.org/0009-0008-9064-7516
Lihong TuDivision of Public Health Service and Safety Assessment, Shanghai Institute of Preventive Medicine, 1380 Zhongshan Rd. W., Changning, Shanghai 200336, China.
Jian ChenNMPA Key Laboratory for Monitoring and Evaluation of Cosmetics, Shanghai Innovation R&D, Testing and Evaluation Technical Service Platform of Cosmetics (22DZ2292100), Department of Evaluation of Cosmetics, Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan Rd. W., Changning, Shanghai 200336, China.ORCID https://orcid.org/0009-0000-1130-098X
Lihong ZhouDivision of Public Health Service and Safety Assessment, Shanghai Institute of Preventive Medicine, 1380 Zhongshan Rd. W., Changning, Shanghai 200336, China.ORCID https://orcid.org/0000-0002-0168-8252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine-disrupting chemicals (EDCs), found in various cosmetic products, interfere with the normal functioning of the endocrine system, impacting hormone regulation and posing risks to human health. Common cosmetic EDCs, such as ultraviolet (UV) filters, parabens, and triclosan, can enter the human body through different routes, including skin absorption. Their presence has been linked to adverse effects on reproduction, immune function, and development. High-throughput in vitro assays, using various human cell lines, were employed to assess the effects of common cosmetic EDCs such as ethylhexyl methoxycinnamate (EHMC), benzophenone-3 (BP-3), homosalate, and parabens. Despite ongoing regulatory efforts, gaps persist in understanding their long-term impacts, particularly when they are present as mixtures or degradation products in the environment. This study focuses on recent in vitro research to investigate the mechanisms through which cosmetic-related EDCs disrupt the endocrine system and other physiological systems. The in vitro findings highlight the broader systemic impact of these chemicals, extending beyond the endocrine system to include immune, reproductive, and cardiovascular effects. This research underscores the importance of developing safer cosmetic formulations and enhancing public health protection, emphasizing the need for stricter regulations.

Indexed as

cosmeticsendocrine disrupting chemicalsmechanismsvitro studies

Identifiers

PMID39659890
PMCPMC11631346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.