Evidence map›Paper›PMID 39659842›Full record

ArticleMaterials today. Bio2024

Injectable hyaluronate-L- cysteine gel potentiates photothermal therapy in osteosarcoma via vorinostat-copper cell death.

Sizhen Wang, Hanzhe Zhang, Tianheng Chen, Weiwei Jiang, Feng Wang, Yuhao Yu, Beibei Guo, Jia Xu, Feng Yang, Qinglin Kang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sizhen WangDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
Hanzhe ZhangDepartment of Orthopaedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People's Republic of China.
Tianheng ChenDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
Weiwei JiangDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
Feng WangDepartment of Orthopaedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People's Republic of China.
Yuhao YuDepartment of Orthopaedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People's Republic of China.
Beibei GuoDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
Jia XuDepartment of Orthopaedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People's Republic of China.
Feng YangDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
Qinglin KangDepartment of Orthopaedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People's Republic of China.
Zhiqiang MaDepartment of Inorganic Chemistry, Pharmacy School, Naval Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis for osteosarcoma patients, a devastating malignancy affecting young individuals, remains grim despite multimodal therapeutic advances. Recently, the advent of cuproptosis, a novel programmed cell death, offers hope in fighting osteosarcoma. In this study, we introduce SAHA

Indexed as

CuproptosisInjectable hydrogelOsteosarcomaPhototherapyVorinostat

Identifiers

PMID39659842
PMCPMC11629197

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.