Evidence map›Paper›PMID 39659834›Full record

ArticleNeuro-oncology advances

Establishment of a brain tumor consortium of Africa: Advancing collaborative research and advocacy for brain tumors in Africa.

Lateef A Odukoya, Kwadwo Darko, Francis Zerd, Nathalie C Ghomsi, Gloria Kabare, David O Kamson, Jeanette E Eckel-Passow, Robert B Jenkins, Gaspar J Kitange, Andrea O Akinjo and 30 more

Abstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

Lateef A OdukoyaDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, New York, USA.
Kwadwo DarkoDepartment of Neurosurgery, Korle-Bu Teaching Hospital, Accra, Ghana.ORCID https://orcid.org/0000-0002-7734-195X
Francis ZerdMortuary and Forensic Department, Benjamin Mkapa Hospital, Dodoma, Tanzania.
Nathalie C GhomsiDepartment of Neurosurgery, Université Félix Houphouet Boigny, Abidjan, Côte d'Ivoire.
Gloria KabareNeurosurgery Department, Aga Khan University Hospital, Nairobi, Kenya.
David O KamsonDepartment of Oncology and Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Jeanette E Eckel-PassowDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, New York, USA.
Robert B JenkinsDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, New York, USA.ORCID https://orcid.org/0000-0002-4049-694X
Gaspar J KitangeDivision of Neuro-Oncology Research, The Hormel Institute, University of Minnesota, Austin, Minnesota, USA.
Andrea O AkinjoAnatomic and Molecular Pathology, Lagos University Teaching Hospital, Lagos, Nigeria.
Kabir B BadmosAnatomic and Molecular Pathology, Lagos University Teaching Hospital, Lagos, Nigeria.
Olufemi BankoleNeurosurgery Unit, Department of Surgery, College of Medicine, University of Lagos, Lagos, Nigeria.
Olufemi E IdowuNeurosurgery Unit, Department of Surgery, Lagos State University Teaching Hospital and Lagos State University College of Medicine Ikeja, Lagos, Nigeria.
Claire KarekeziNeurosurgery Unit, Department of Surgery, Rwanda Military Referral and Teaching Hospital, University of Rwanda, Kigali, Rwanda.ORCID https://orcid.org/0000-0002-7183-899X
Elias EdrickDepartment of Pathology, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Chukwuyem EkhatorDepartment of Neuro-Oncology, New York Institute of Technology, College of Osteopathic Medicine, New York, New York, USA.
Victoria M KatasiDepartment of Pediatric Oncology and Hematology, Mulago National Referral Hospital, Mulago, Uganda.
Desmond A BrownDepartment of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Jason HuseDepartment of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID https://orcid.org/0000-0003-4514-0640
Henry LlewellynDepartment of Global Health & Social Medicine, King's College London, London, UK.
Margreth MagamboDepartment of Radiology, Bugando Medical Centre, Mwanza, Tanzania.
Michael MagohaDepartment of Surgery, University of Nairobi, Nairobi, Kenya.
Umaru BarrieDepartment of Neurosurgery, NYU Grossman School of Medicine, New York, New York, USA.
Advera NgaizaDepartment of Anatomical Pathology, Muhimbili National Hospital, Muhimbili, Tanzania.
Arsene D NyalundjaCenter for Tropical Diseases and Global Health, Faculty of Medicine, Université Catholique de Bukavu, Bugabo, Democratic Republic of Congo.
Minda OkemwaDepartment of Human Pathology, University of Nairobi, Nairobi, Kenya.
Lawrence Osei-TutuPaediatric Oncology Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Bernard PetershieDepartment of Pathology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
W Elorm YevudzaDepartment of Neurosurgery, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Charles C AnunobiAnatomic and Molecular Pathology, Lagos University Teaching Hospital, Lagos, Nigeria.
Liadi TiamiyuDepartment of Neurological Surgery, Federal Medical Centre, Abeokuta, Nigeria.
Gbetoho Fortuné GankpeDepartment of Neurosurgery, Centre National Hospitalier Universitaire Hubert Koutoukou, Cotonou, Benin.
Kashaigili HeronimaDepartment of Oncology, Bugando Medical Centre, Mwanza, Tanzania.
Dominique HigginsDepartment of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kristin SchroederPediatric Oncology, Bugando Medical Centre, Mwanza, Tanzania.
Teddy TotimehDepartment of Surgery, Accra Medical Centre, Accra, Ghana.
James BalogunDivision of Neurosurgery, Department of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID https://orcid.org/0000-0002-0737-5265
Beverly CheseremNeurosurgery Department, Aga Khan University Hospital, Nairobi, Kenya.
Arnold B EtameDepartment of Neuro-Oncology, Moffitt Cancer Centre, University of South Florida, Tampa, Florida, USA.
Ekokobe FonkemDepartment of Neurology, Medical College of Wisconsin, Milwaukee, Wisconson, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Brain tumors represent a significant global health challenge, with rising incidence and mortality impacting individuals worldwide and contributing to cancer-related morbidity and mortality. In Africa, this burden is exacerbated by limited access to advanced diagnostics, treatment options, and multidisciplinary care, compounded by the absence of standardized cancer registration and tumor biobanking. The introduction of molecular diagnostics, as outlined in the 2021 World Health Organization central nervous system (CNS) tumor classification, adds complexity to brain tumor management, particularly in regions with scarce resources. Methods: To address these issues, the Brain Tumor Consortium for Africa (BTCA) was established in 2023, bringing together experts to improve CNS tumor diagnosis, patient care, and research. The initial project, conducted via an electronic questionnaire, aimed to assess neuro-oncology capacity across Sub-Saharan Africa. Results: The study revealed significant gaps, with a limited number of institutions incorporating molecular subtyping into their diagnostic algorithms. The consortium's efforts focus on enhancing local data use, informing public policy, and promoting collaboration to advance neuro-oncology practices in Africa. By fostering a network enlisting the expertise of collaborators in the fields of neurosurgery, neurology, neuropathology, anatomic pathology, and medical and radiation oncology, the BTCA seeks to improve brain tumor management through better diagnostics, infrastructure, and policy advocacy. Future directions include expanding molecular diagnostic capabilities, standardizing brain tumor biobanking, enhancing data collection, and advocating for improved brain tumor care in national health agendas. Conclusions: The BTCA represents a pioneering model of collaboration and innovation in addressing the unique challenges of brain tumor care in Africa.

Indexed as

brain tumorsCNS tumor registryglobal neurosurgerymolecular subtypingsub-Saharan Africa

Identifiers

PMID39659834
PMCPMC11631193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.