Evidence map›Paper›PMID 39659803›Full record

ArticleFrontiers in physiology2024

Direct effects of remote ischemic preconditioning on post-exercise-induced changes in kynurenine metabolism.

Paulina Brzezińska, Jan Mieszkowski, Błażej Stankiewicz, Tomasz Kowalik, Joanna Reczkowicz, Bartłomiej Niespodziński, Aleksandra Durzyńska, Konrad Kowalski, Andżelika Borkowska, Jędrzej Antosiewicz and 1 more

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Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Paulina BrzezińskaDepartment of Gymnastics and Dance, Gdańsk University of Physical Education and Sport, Gdańsk, Poland.
Jan MieszkowskiDepartment of Gymnastics and Dance, Gdańsk University of Physical Education and Sport, Gdańsk, Poland.
Błażej StankiewiczDepartment of Theory and Methodology of Physical Education and Sport, Faculty of Health Sciences and Physical Education, Kazimierz Wielki University, Bydgoszcz, Poland.
Tomasz KowalikDepartment of Theory and Methodology of Physical Education and Sport, Faculty of Health Sciences and Physical Education, Kazimierz Wielki University, Bydgoszcz, Poland.
Joanna ReczkowiczDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdańsk, Gdańsk, Poland.
Bartłomiej NiespodzińskiDepartment of Biological Foundations of Physical Education, Faculty of Health Sciences and Physical Education, Kazimierz Wielki University, Bydgoszcz, Poland.
Aleksandra DurzyńskaFaculty of Health Sciences, University of Lomza, Łomża, Poland.
Konrad KowalskiDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdańsk, Gdańsk, Poland.
Andżelika BorkowskaDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdańsk, Gdańsk, Poland.
Jędrzej AntosiewiczDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdańsk, Gdańsk, Poland.
Andrzej KochanowiczDepartment of Gymnastics and Dance, Gdańsk University of Physical Education and Sport, Gdańsk, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Tryptophan (TRP) degradation through the kynurenine pathway is responsible for converting 95% of free TRP into kynurenines, which modulate skeletal muscle bioenergetics, immune and central nervous system activity. Therefore, changes in the kynurenines during exercise have been widely studied but not in the context of the effects of remote ischemic preconditioning (RIPC). In this study, we analyzed the effect of 14-day RIPC training on kynurenines and TRP in runners after running intervals of 20 × 400 m. Methods: In this study, 27 semi-professional long-distance runners were assigned to two groups: a RIPC group performing 14 days of RIPC training (n = 12), and a placebo group, SHAM (n = 15). Blood was collected for analysis before, immediately after, and at 6 h and 24 h after the run. Results: After the 14-day RIPC/SHAM intervention, Conclusion: RIPC modulates post-exercise changes in XANA and TRP levels, which can affect brain health, yet further research is needed.

Indexed as

kynurenic acidlimb ischemialong-distance runnerneuro-protective metabolitestryptophanxanthurenic acid

Identifiers

PMID39659803
PMCPMC11628380

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