Evidence map›Paper›PMID 39659739›Full record

ArticleThe journal of allergy and clinical immunology. Global2025

Sinusitis and rhinitis among US veterans deployed to Southwest Asia and Afghanistan after September 11, 2001.

Jennifer Maccarone, Carrie A Redlich, Andrew Timmons, Anna M Korpak, Nicholas L Smith, Karen S Nakayama, Coleen P Baird, Paul Ciminera, Farrah Kheradmand, Vincent S Fan and 12 more

Registry-linked trialAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. Global, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02825654 (CSP #595 - Pulmonary Health and Deployment to Southwest Asia and Afghanistan), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02825654 enrolling by invitationnot on this map

CSP #595 - Pulmonary Health and Deployment to Southwest Asia and Afghanistan

Typeobservational_patient_registrySponsorVA Office of Research and DevelopmentRan2018 to 2029Enrolled6,200ConditionsPulmonary Function
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Jennifer MaccaronePulmonary, Allergy, Sleep and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, West Roxbury, Mass.
Carrie A RedlichOccupational and Environmental Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Conn.
Andrew TimmonsSeattle Epidemiologic Research and Information Center, Department of Veteran Affairs Office of Research and Development, VA Puget Sound Health Care System Seattle Division, Seattle, Wash.
Anna M KorpakSeattle Epidemiologic Research and Information Center, Department of Veteran Affairs Office of Research and Development, VA Puget Sound Health Care System Seattle Division, Seattle, Wash.
Nicholas L SmithSeattle Epidemiologic Research and Information Center, Department of Veteran Affairs Office of Research and Development, VA Puget Sound Health Care System Seattle Division, Seattle, Wash.
Karen S NakayamaDepartment of Epidemiology, University of Washington, Seattle, Wash.
Coleen P BairdMedical Science Affiliates, Columbia, Md.
Paul CimineraHealth Services Policy and Oversight, Office of the Assistant Secretary of Defense for Health Affairs, Washington, DC.
Farrah KheradmandDepartment of Medicine, Michael E. DeBakey VA Medical Center, Houston, Tex.
Vincent S FanVA Puget Sound Health Care System Seattle Division, Seattle, Wash.
Jaime E HartBrigham and Women's Hospital Channing Division of Network Medicine, Boston, Mass.
Petros KoutrakisDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, Mass.
Ware G KuschnerVA Palo Alto Health Care System, Palo Alto, Calif.
Octavian C IoachimescuClement J. Zablocki VA Medical Center, Milwaukee, Wis.
Michael JerrettUniversity of California Los Angeles Jonathan and Karin Fielding School of Public Health, Los Angeles, Calif.
Philippe R MontgrainVA San Diego Health Care System, San Diego, Calif.
Susan P ProctorUS Army Research Institute of Environmental Medicine, Natick, Mass.
Christine H WendtPulmonary, Allergy, Critical Care and Sleep Medicine, Minneapolis VA Medical Center, Minneapolis, Minn.
Cherry WongtrakoolAtlanta VA Medical Center, Decatur, Ga.
Emily S WanPulmonary, Allergy, Sleep and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, West Roxbury, Mass.
Paul D BlancSan Francisco VA Health Care System, San Francisco, Calif.
Eric GarshickPulmonary, Allergy, Sleep and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, West Roxbury, Mass.

Funding

Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
NIEHS NIH HHS P30 ES030285
6 · The paper itself

Abstract

Background: Post-9/11 veterans were exposed to environmental and occupational pollutants during deployment. Objective: Our aim was to determine associations between deployment-related exposures and sinusitis and rhinitis. Methods: Between April 2018 and March 2020, veterans with land-based deployment after 9/11 who were living within 25 miles of 6 Department of Veteran Affairs medical centers were randomly chosen by using a Defense Manpower Data Center roster. Participants completed interviewer-administered questionnaires, which included a 32-item deployment exposure battery and self-report of rhinitis and health professional-diagnosed sinusitis. Exposure categories included burn pit smoke, combustion engine exhaust/ground dust, other open combustion sources, toxicants, and military job-related VGDF. Each item was scored on the basis of frequency and duration of exposure; ordinal scores were summed and scaled to 100 within each category. Odds ratios (ORs) were estimated using logistic regression for sinusitis and rhinitis separately. ORs were scaled per 20-point exposure score. Results: Among the 1960 participants, the incidences of sinusitis and rhinitis with onset during deployment were 2.1% and 3.6%, respectively; the incidences of postdeployment onset were 5.1% and 5.6%, respectively. Toxicant exposure consisted mainly of "applying pesticide, insecticide, or repellent to your own skin or to your own clothing" and was associated with rhinitis with onset during deployment (OR = 1.50 [95% CI = 1.31-1.84]) and onset after deployment (OR = 1.21 [95% CI = 0.93-1.50]). There were no associations with burn pit smoke or other exposure categories. Conclusion: Veterans with deployment exposures to toxicants were at increased risk of rhinitis, particularly during deployment. The clinical evaluation of postdeployment veterans should address rhinitis as a deployment-related condition.

Indexed as

chronic rhinosinusitisenvironmental exposuremilitaryoccupational exposurerhinitisSinusitisveterans

Identifiers

PMID39659739
PMCPMC11629329

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.