Evidence map›Paper›PMID 39659672›Full record

ArticleBiology methods & protocols2024

Development of a new breath collection method for analyzing volatile organic compounds from intubated mouse models.

Alastair Taylor, Sylvia Blum, Madeleine Ball, Owen Birch, Hsuan Chou, Julia Greenwood, Shane Swann, Lara Pocock, Max Allsworth, Billy Boyle and 1 more

Abstract read
In one paragraph

Article in Biology methods & protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alastair TaylorOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.
Sylvia BlumBoehringer Ingelheim, Biberach, 88397, Germany.
Madeleine BallOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.ORCID https://orcid.org/0000-0002-6150-0485
Owen BirchOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.
Hsuan ChouOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.
Julia GreenwoodOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.
Shane SwannOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.
Lara PocockOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.
Max AllsworthOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.
Billy BoyleOwlstone Medical, Cambridge, CB4 0GA, United Kingdom.
Kerstin Geillinger-KaestleBoehringer Ingelheim, Biberach, 88397, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new pre-clinical method for capturing breath samples from intubated mice is presented. This method significantly reduces background levels, allowing more accurate measurements of VOCs originating from the breath ("on-breath") as opposed to background contamination. The method was developed by integrating industry-standard volatile-capturing sorbent tubes with respiratory mechanics measurement equipment (flexiVent

Indexed as

breath analysismouse breathmouse modelVOC analysisvolatile organic compounds

Identifiers

PMID39659672
PMCPMC11631442

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.