Evidence map›Paper›PMID 39659629›Full record

ArticleCirculation reports2024

Impact of Nutritional Status and Cardiopulmonary Exercise Testing-Based Exercise Education on Long-Term Outcomes in Acute Coronary Syndrome - Insights From the Mie ACS Registry.

Hiroaki Murakami, Naoki Fujimoto, Keishi Moriwaki, Hiromasa Ito, Akihiro Takasaki, Kiyotaka Watanabe, Atsushi Kambara, Naoto Kumagai, Takashi Omura, Tairo Kurita and 2 more

Abstract read
In one paragraph

Article in Circulation reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hiroaki MurakamiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine Mie Japan.
Naoki FujimotoDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine Mie Japan.
Keishi MoriwakiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine Mie Japan.
Hiromasa ItoDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine Mie Japan.
Akihiro TakasakiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine Mie Japan.
Kiyotaka WatanabeDepartment of Cardiology, Suzuka General Hospital Mie Japan.
Atsushi KambaraDepartment of Cardiovascular Surgery, Okanami General Hospital Mie Japan.
Naoto KumagaiDepartment of Cardiology, Nagai Hospital Mie Japan.
Takashi OmuraDepartment of Cardiology, Kuwana City Medical Center Mie Japan.
Tairo KuritaDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine Mie Japan.
Ryo MomosakiDepartment of Rehabilitation Medicine, Mie University Graduate School of Medicine Mie Japan.
Kaoru DohiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine Mie Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Exercise training based on cardiopulmonary exercise testing (CPET) improves outcomes in patients with acute coronary syndrome (ACS), while nutritional status is also crucial. This study evaluated CPET implementation and the impacts of clinical parameters, including CPET and nutritional status, on 2-year outcomes in ACS patients. Methods and Results: Data from 2,621 ACS patients enrolled in the Mie ACS registry were analyzed. Of these, 938 were hospitalized in CPET-equipped facilities, while 1,683 were not. Nutritional status was assessed using controlling nutritional status (CONUT) score. Cox regression analysis evaluated the associations between nutritional status, CPET-based exercise education, and 2-year prognosis. Among the 938 patients in CPET facilities, 359 underwent CPET and received exercise education. During the 2-year follow up, 60 all-cause deaths occurred. Univariate Cox regression revealed that CPET implementation was associated with lower all-cause mortality. Other predictors included hemoglobin levels, age, hospitalization length, Killip class ≥2, mechanical support, and malnutrition. In multivariate Cox regression, CPET implementation remained an independent predictor of mortality (hazard ratio 0.47; P=0.04). However, when nutritional status was included, moderate to severe malnutrition emerged as an independent predictor of all-cause mortality (hazard ratio 2.47; P=0.02), diminishing the significance of CPET (P=0.058). Conclusions: Moderate to severe malnutrition is a powerful independent prognostic factor for mortality in the Mie ACS registry. CPET implementation may enhance survival in ACS patients.

Indexed as

Acute coronary syndromeCardiopulmonary exercise testingCONUT scorePrognosis

Identifiers

PMID39659629
PMCPMC11626020

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.