Evidence map›Paper›PMID 39659435›Full record

ArticleF1000Research2024

Laboratory findings predictive of critical illness in hospitalized COVID-19 patients in Tunisia.

Donia Belkhir, Hana Blibech, Line Kaabi, Saoussen Miladi, Mohamed Aymen Jebali, Jalloul Daghfous, Nadia Mehiri, Ahmed Laatar, Nozha Ben Salah, Houda Snene and 1 more

Abstract read
In one paragraph

Article in F1000Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Donia BelkhirPulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.ORCID https://orcid.org/0009-0005-5868-0293
Hana BlibechPulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.ORCID https://orcid.org/0000-0003-4979-8853
Line KaabiPulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.
Saoussen MiladiRheumatology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.ORCID https://orcid.org/0000-0002-3596-8025
Mohamed Aymen JebaliPulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.
Jalloul DaghfousPulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.
Nadia MehiriPulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.
Ahmed LaatarRheumatology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.
Nozha Ben SalahPulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.
Houda SnenePulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.
Bechir LouzirPulmonology, University Hospital Center Mongi Slim, La Marsa, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: COVID-19 disease has spread rapidly worldwide, causing high mortality. Accessible biomarkers capable of early identification of patients at risk of severe form are needed in clinical practice. The aim of the study was to determine the biological markers that predict a critical condition. Methods: Retrospective study including patients with confirmed COVID-19 hospitalized between September 2020 and June 2021. The primary endpoint was progression to critical status within 7 days from admission. We defined two groups:Critical group: Patients who developed a critical condition or died or transferred to the ICU before or at 7 Results: Our study included 456 patients, with a sex ratio of 1.32 and an average age of 62 years. At the 7 Conclusions: Our results show the predictive value of lymphopenia, thrombocytopenia, high NLR and CRP levels to evaluate the prognosis of COVID-19 pneumonia. A prognostic score could be proposed for guiding clinical care and improving patient outcomes.

Indexed as

BiomarkersCOVID-19Critical IllnessHospitalizationSARS-CoV-2AgedC-Reactive ProteinCreatinineFemaleFibrin Fibrinogen Degradation ProductsHumansMaleMiddle AgedPrognosisRetrospective StudiesTunisiaBiomarkersC-Reactive ProteinCreatinineFibrin Fibrinogen Degradation Productsfibrin fragment DAdult respiratory distress syndromeBiomarkersCOVID-19Critical illnessPrognosisViral pneumonia

Identifiers

PMID39659435
PMCPMC11628936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.