Evidence map›Paper›PMID 39659319›Full record

ArticleCureus2024

Intravascular Large B-cell Lymphoma Associated With Hemophagocytosis as a Cause of Fever of Unknown Origin: A Review of Literature.

Shula Staessens, Nathan De Beule, Els Van Nedervelde, Sabine Allard

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shula StaessensInternal Medicine, Universitair Ziekenhuis Brussel, Brussels, BEL.
Nathan De BeuleClinical Hematology, Universitair Ziekenhuis Brussel, Brussels, BEL.
Els Van NederveldeInternal Medicine and Infectiology, Universitair Ziekenhuis Brussel/Vrije Universiteit Brussel, Brussels, BEL.
Sabine AllardInternal Medicine and Infectiology, Universitair Ziekenhuis Brussel, Brussels, BEL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 53-year-old woman was hospitalized due to a fever of unknown origin for three weeks. Given the presence of fever and fatigue, the laboratory findings, and a bone marrow biopsy confirming hemophagocytic lymphohistiocytosis (HLH), a hematological malignancy was suspected. Peripheral lymphocytic typing, bone marrow biopsy, and imaging could not identify an underlying cause of HLH. Therefore, an abdominal wall deep skin biopsy was performed, showing an intravascular large B-cell lymphoma (IVLBCL). Intravascular large B-cell lymphoma should be considered in all patients with fever of unknown origin, especially in the context of HLH. Diagnosis of IVLBCL requires a deep skin biopsy or a biopsy of an affected organ.

Indexed as

deep skin biopsyfever of unknown origin (fuo)intravascular large b-cell lymphomalymphohistiocytic hemophagocytosissecondary hlh

Identifiers

PMID39659319
PMCPMC11630421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.