Evidence map›Paper›PMID 39659289›Full record

ArticleOrthopaedic surgery2025

Vertebral Column Decancellation for Correcting Cervicothoracic Kyphotic Deformity in Patients With Ankylosing Spondylitis.

Han Yu, Qi Wang, Yiming Fan, Dengbin Qi, Tianhao Wang, Bing Li, Yi Huang, Ze Wang, Chao Xue, Guoquan Zheng

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Article in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Han YuMedical School of Chinese People's Liberation Army, Beijing, China.ORCID https://orcid.org/0009-0002-1950-8296
Qi WangDepartment of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Yiming FanMedical School of Chinese People's Liberation Army, Beijing, China.
Dengbin QiDepartment of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Tianhao WangDepartment of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Bing LiMedical School of Chinese People's Liberation Army, Beijing, China.ORCID https://orcid.org/0000-0002-4389-0926
Yi HuangNankai University School of Medicine, Nankai University, Tianjin, China.ORCID https://orcid.org/0000-0001-9140-3881
Ze WangMedical School of Chinese People's Liberation Army, Beijing, China.
Chao XueDepartment of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Guoquan ZhengDepartment of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing, China.ORCID https://orcid.org/0009-0005-1860-2872

Funding

Beijing Nova Program 20230484464
6 · The paper itself

Abstract

objectiveSurgery to correct the cervicothoracic kyphotic deformity in ankylosing spondylitis (AS) can be associated with serious neurovascular risks. According to the literature, there are no clinical reports documenting the use of vertebral column decancellation (VCD) in the treatment of cervicothoracic kyphotic deformity in patients with AS. The purpose of the present study was to retrospectively analyze and evaluate the effect of VCD on cervicothoracic kyphotic deformity in patients with AS.

methodsRecords of eight patients with cervicothoracic kyphotic deformity who underwent VCD at C7 in our institution were retrospectively reviewed. The mean duration of clinical follow-up after surgery was 19 months. The cervical lordosis (CL) and C2-C7 sagittal vertical axis (SVA) were meticulously measured on full-length spine radiographs. The chin-brow vertical angle (CBVA) was measured on clinical photographs. Outcome measures utilized included the Neck Disability Index (NDI), the Japanese Orthopaedic Association (JOA) Score, and a Visual Analog Scale (VAS) for neck pain. The data analysis was performed using SPSS version 26.0 for Windows. For paired data adhering to a normal distribution, we utilized paired sample t-tests to analyze preoperative and postoperative imaging parameters. Statistical significance was established at a p value threshold of < 0.01.

resultsAll eight patients successfully completed the surgery. With an average VCD osteotomy angle of 47.6° ± 8.1° (±SD), the mean preoperative CBVA was 81.1° ± 17.6° (±SD), while the immediate postoperative value was 19.9° ± 5.7° (±SD). The overall average correction was 61.2° ± 18.9°. The mean preoperative cervical sagittal imbalance was 93.4 ± 27.3 mm (±SD), while the immediate postoperative value was 40.2 ± 18.9 mm (±SD). The overall average correction was 53.2 ± 28.1 mm. None of the eight patients experienced intraoperative complications, including nerve or vascular injury, cerebrospinal fluid leakage, or any other related complications. In the cohort of eight patients, the mean values for estimated blood loss, surgical time, and hospital stay were 1313 mL, 248 min, and 18 days, respectively. In comparison to preoperative scores, statistically significant improvement was noted in all patients in the postoperative period with regard to NDI, JOA, and VAS (p < 0.01, using a paired t-test).

conclusionThe VCD procedure proves to be a dependable and efficient approach for addressing cervicothoracic kyphotic deformities. It achieves remarkable corrections in cervical kyphosis and CBVA.

trial registrationChinese Clinical Trial Registry: 2400090375.

Indexed as

Cervical VertebraeKyphosisSpondylitis, AnkylosingThoracic VertebraeAdultFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomeankylosing spondylitiscervical osteotomycervicothoracic kyphoticvertebral column decancellation

Identifiers

PMID39659289
PMCPMC11872378

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.