Evidence map›Paper›PMID 39659141›Full record

SynthesisThe British journal of psychiatry : the journal of mental science2025

Personality disorders, violence and antisocial behaviour: updated systematic review and meta-regression analysis.

Rachel T S Chow, Rongqin Yu, John R Geddes, Seena Fazel

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The British journal of psychiatry : the journal of mental science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Divergent disinhibition profiles linked to externalizing psychopathology.Journal of psychopathology and clinical science · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Implicit and explicit self-concepts of forgiveness in women with borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rachel T S ChowDepartment of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
Rongqin YuDepartment of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.ORCID https://orcid.org/0000-0001-7315-3348
John R GeddesDepartment of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
Seena FazelDepartment of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.ORCID https://orcid.org/0000-0002-5383-5365

Funding

Wellcome TrustWellcome Trust 202836/Z/16/Z
6 · The paper itself

Abstract

backgroundLinks between personality disorders and antisocial outcomes has not examined individual personality disorders, and the contribution of comorbidities remain uncertain. Previous systematic reviews are dated.

aimsTo synthesise evidence from observational studies on the risk of antisocial outcomes and recidivism associated with personality disorders.

methodWe searched six bibliographic databases (up to March 2024) for observational studies examining the risk of antisocial behaviour, interpersonal violence and recidivism in individuals diagnosed with personality disorders, compared to controls. We explored sources of heterogeneity using subgroup analyses and meta-regression.

resultsWe identified 21 studies involving 83 418 individuals with personality disorders from 10 countries examining antisocial and violent outcomes (Aim 1), and 39 studies of 14 131 individuals from 13 countries with recidivism (or repeat offending) as the outcome (Aim 2). We found increased risks of violence among individuals with any personality disorder (odds ratio 4.5, 95% CI 3.0-6.7), particularly antisocial personality disorder (odds ratio 7.6, 95% CI 5.1-11.5) and borderline personality disorder (odds ratio 2.6, 95% CI 1.8-3.9). Individuals with any personality disorder (odds ratio 2.3, 95% CI 2.0-2.6) and antisocial personality disorder (odds ratio 2.8, 95% CI 1.6-4.9) also demonstrated an elevated risk of recidivism. Personality disorder types and comorbid substance use disorder were associated with between-study heterogeneity.

conclusionsThe assessment and management of personality disorders should be considered as part of violence prevention strategies. Improving identification and treatment of comorbid substance misuse may reduce adverse outcomes in individuals with personality disorders.

Indexed as

Antisocial Personality DisorderPersonality DisordersRecidivismViolenceComorbidityHumansforensic psychiatrymeta-analysisobservational studyPersonality disorderssystematic review

Identifiers

PMID39659141
PMCPMC12278050

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.