Evidence map›Paper›PMID 39658948›Full record

ArticleJournal of neurophysiology2025

Center of mass states render multijoint torques throughout standing balance recovery.

Kristen L Jakubowski, Giovanni Martino, Owen N Beck, Gregory S Sawicki, Lena H Ting

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Kristen L JakubowskiWallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States.ORCID 0000-0003-3435-8353
Giovanni MartinoDepartment of Biomedical Sciences, University of Padova, Padua, Italy.
Owen N BeckDepartment of Kinesiology and Health Education, University of Texas at Austin, Austin, Texas, United States.ORCID 0000-0002-1802-6036
Gregory S SawickiGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States.ORCID 0000-0002-5588-6297
Lena H TingWallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, United States.ORCID 0000-0001-6854-9444

Funding

Neuromechanical Modeling of Postural Responses:Mechanisms of Balance Impairments in Parkinson's DiseaseR01HD046922 · NICHD · GEORGIA INSTITUTE OF TECHNOLOGY · PI Michael Robert Borich, Lena H Ting · 2004 to 2026
$7.7M
Multiscale models of proprioceptive encoding to reveal mechanisms of impaired sensorimotor controlR01HD090642 · NICHD · EMORY UNIVERSITY · PI COPE, TIMOTHY C, SAWICKI, GREGORY STEPHEN · 2016 to 2025
$4.9M
Individual-specific engagement of cortical resources for standing balance control in aging and post strokeR01AG072756 · NIA · EMORY UNIVERSITY · PI Michael Robert Borich, Lena H Ting · 2022 to 2026
$3.0M
Physiologically-inspired exoskeleton controller to enhance human balanceF32HD112128 · NICHD · EMORY UNIVERSITY · PI Kristen L Jakubowski · 2024 to 2026
$164k
Linking muscle-tendon dynamics and energetics to inform exoskeleton design for improved locomotor economy in aging.F32AG063460 · NIA · GEORGIA INSTITUTE OF TECHNOLOGY · PI BECK, OWEN · 2019 to 2021
$151k
NIA NIH HHS F32 AG063460NIA NIH HHS R01 AG072756NICHD NIH HHS F32 HD112128NICHD NIH HHS R01 HD046922NICHD NIH HHS R01 HD090642
6 · The paper itself

Abstract

Successful reactive balance control requires coordinated modulation of hip, knee, and ankle torques. Stabilizing joint torques arise from neurally-mediated feedforward tonic muscle activation that modulates muscle short-range stiffness, which provides instantaneous "mechanical feedback" to the perturbation. In contrast, neural feedback pathways activate muscles in response to sensory input, generating joint torques after a delay. However, the specific contributions from feedforward and feedback pathways to the balance-correcting torque response are poorly understood. As feedforward- and feedback-mediated torque responses to balance perturbations act at different delays, we modified the sensorimotor response model (SRM), previously used to analyze the muscle activation response, to reconstruct joint torques using parallel feedback loops. Each loop is driven by the same information, center of mass (CoM) kinematics, but each loop has an independent delay. We evaluated whether a torque-SRM could decompose the reactive torques during balance-correcting responses to backward support surface translations at four magnitudes into the instantaneous "mechanical feedback" torque modulated by feedforward neural commands before the perturbation and neurally-delayed feedback components. The SRM accurately reconstructed torques at the hip, knee, and ankle, across all perturbation magnitudes (

Indexed as

Biomechanical PhenomenaFeedback, SensoryPostural BalanceAnkle JointHip JointHumansKnee JointModels, NeurologicalMuscle, SkeletalStanding PositionTendonsTorquefeedforward controlmotor controlpostural controlsensorimotor feedbacktendon stiffness

Identifiers

PMID39658948
PMCPMC11967846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.