Evidence map›Paper›PMID 39658889›Full record

ArticleThe Journal of small animal practice2025

Meningeal null cell lymphoma causing diffuse pachymeningeal contrast enhancement in a dog.

M Madden, N Israeliantz, A Malbon, C Piccinelli, K Marioni-Henry, T Schwarz, A Suñol

Abstract readCase Reports
In one paragraph

Article in The Journal of small animal practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M MaddenHospital for Small Animals, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-7212-4633
N IsraeliantzHospital for Small Animals, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
A MalbonHospital for Small Animals, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
C PiccinelliHospital for Small Animals, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
K Marioni-HenryFitzpatrick Referrals, Godalming, UK.
T SchwarzHospital for Small Animals, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
A SuñolHospital Veterinaria del Mar, IVC Evidensia, Barcelona, Spain.ORCID 0000-0003-0985-6959

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse pachymeningeal contrast enhancement is an uncommon imaging finding in dogs and current understanding of its aetiologies in veterinary medicine is limited. A 2-year-old female neutered Pug presented with chronic progressive vestibular signs, facial nerve paralysis, obtundation and episodic decerebellate rigidity. A magnetic resonance imaging study of the head revealed diffuse pachymeningeal thickening and contrast enhancement involving the caudal fossa and falx cerebri. Cerebrospinal fluid analysis revealed marked neutrophilic pleocytosis. Infectious disease testing was negative and a tentative diagnosis of intracranial idiopathic hypertrophic pachymeningitis was made. Immunosuppressive treatment resulted in a short period of clinical improvement. The patient subsequently suffered multiple relapses which failed to respond to alternative immunosuppressive strategies, necessitating euthanasia. Histopathological findings supported a meningeal null cell lymphoma. While rare, neoplastic causes of diffuse pachymeningeal thickening and contrast enhancement should be considered.

Indexed as

Dog DiseasesMeningeal NeoplasmsAnimalsDogsFemaleImmunosuppressive AgentsMagnetic Resonance ImagingMeningitisImmunosuppressive Agents

Identifiers

PMID39658889
PMCPMC11915479

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.