Evidence map›Paper›PMID 39658561›Full record

ArticleNPJ digital medicine2024

Predicting control of cardiovascular disease risk factors in South Asia using machine learning.

Anna Reuter, Mohammed K Ali, Viswanathan Mohan, Lydia Chwastiak, Kavita Singh, K M Venkat Narayan, Dorairaj Prabhakaran, Nikhil Tandon, Nikkil Sudharsanan

Abstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna ReuterGerman Federal Institute of Population Research, Wiesbaden, Germany.ORCID http://orcid.org/0000-0002-3087-7415
Mohammed K AliEmory Global Diabetes Research Center, Woodruff Health Sciences Center and Emory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0001-7266-2503
Viswanathan MohanDr. Mohan's Diabetes Specialties Centre, Chennai, India.
Lydia ChwastiakDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Kavita SinghHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.
K M Venkat NarayanEmory Global Diabetes Research Center, Woodruff Health Sciences Center and Emory University, Atlanta, GA, USA.
Dorairaj PrabhakaranCentre for Control of Chronic Conditions, Public Health Foundation of India, Gurgaon, India.
Nikhil TandonDepartment of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.
Nikkil SudharsananHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany. nikkil.sudharsanan@tum.de.ORCID http://orcid.org/0000-0003-1710-4634

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
Integrated Care for Co-morbid Depression and Diabetes in IndiaR01MH100390 · NIMH · EMORY UNIVERSITY · PI ALI, MOHAMMED KUMAIL, CHWASTIAK, LYDIA ANN · 2013 to 2017
$2.4M
Building the Asian NCoD Research Network for Regional Research CapacityD43TW008332 · FIC · MONASH UNIVERSITY · PI FISHER, EDWIN B, KADIR, KHALID · 2010 to 2014
$1.0M
FIC NIH HHS D43 TW008332FIC NIH HHS R24 TW007988NHLBI NIH HHS HHSN268200900026CNIMH NIH HHS R01 MH100390U.S. Department of Health & Human Services | NIH | Fogarty International Center (FIC) D43TW008332
6 · The paper itself

Abstract

A substantial share of patients at risk of developing cardiovascular disease (CVD) fail to achieve control of CVD risk factors, but clinicians lack a structured approach to identify these patients. We applied machine learning to longitudinal data from two completed randomized controlled trials among 1502 individuals with diabetes in urban India and Pakistan. Using commonly available clinical data, we predict each individual's risk of failing to achieve CVD risk factor control goals or meaningful improvements in risk factors at one year after baseline. When classifying those in the top quartile of predicted risk scores as at risk of failing to achieve goals or meaningful improvements, the precision for not achieving goals was 73% for HbA1c, 30% for SBP, and 24% for LDL, and for not achieving meaningful improvements 88% for HbA1c, 87% for SBP, and 85% for LDL. Such models could be integrated into routine care and enable efficient and targeted delivery of health resources in resource-constrained settings.

Identifiers

PMID39658561
PMCPMC11631980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.