Evidence map›Paper›PMID 39658121›Full record

ArticleSaudi medical journal2024

Silent reactivation of Varicella Zoster virus in hemodialysis patients.: A management dilemma.

Bandar A Suliman, Hassan T Alhazmi, Hamzah A Alamri, Ahmed A Aljuhani, Mohammed S Younis, Khalid H Mahallawi, Fayez H Alsehli, Ibrahim T Alomani, Bashayer A Almoutairi, Yasser S Asar and 3 more

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Article in Saudi medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Bandar A SulimanFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Hassan T AlhazmiFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Hamzah A AlamriFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Ahmed A AljuhaniFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Mohammed S YounisFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Khalid H MahallawiFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Fayez H AlsehliFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Ibrahim T AlomaniFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Bashayer A AlmoutairiFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Yasser S AsarFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Mohammed A AlkhailyFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Walaa A MomenaFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.
Waleed H MahallawiFrom the Department of Clinical Laboratory Sciences (Suliman, Alhazmi, Alamri, Aljuhani, Younis) and from the Clinical Nutrition Department (Mumena), College of Applied Medical Sciences, Taibah University; from the Health Affairs Department (Mahallawi), Rehabilitation Hospital, Ministry of Health; from the Madinah Regional Blood Bank (Alsehli), from Madinah Regional Laboratory (Alomani, Almoutairi, Asar), from the Madinah Health Cluster (Alkhaily), Ministry of Health, Al Madina Al Munawarah, Kingdom of Saudi Arabia.ORCID https://orcid.org/0000-0001-6977-9006

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the seroprevalence of Varicella Zoster virus (VZV) immunoglobulin (Ig)G and IgM antibodies among hemodialysis patients (HDP). Additionally, the presence of VZV viral DNA has been investigated for possible reactivation status.

methodsSera from 265 individuals were collected and tested. The study was carried out from November 2023 to February 2024. Enzyme linked immunosorbent assay was accomplished to determine the VZV IgG and IgM antibody levels. The viral DNA was tested by qPCR.

resultsWe found a significantly higher proportion of Host defense peptides (HDP) have positive antibody levels compared to healthy controls (HC) (92.0% of HDP have positive immune responses compared to 79.1% of HC,

conclusionIn conclusion, significantly higher VZV seroprevalence and antibody levels in HDP indicate greater viral exposure than HC. Screening of hemodialysis (HD) to VZV serologically or at the molecular level is most important to avoid the consequences of viral reactivation, especially in those with asymptomatic HDP.

Indexed as

Antibodies, ViralHerpesvirus 3, HumanImmunoglobulin GImmunoglobulin MRenal DialysisVirus ActivationAdultAgedDNA, ViralFemaleHumansHypertensionMaleMiddle AgedSeroepidemiologic StudiesAntibodies, ViralDNA, ViralImmunoglobulin GImmunoglobulin Mhemodialysis patientsimmunosuppressionreactivationVaricella-zoster virus

Identifiers

PMID39658121
PMCPMC11629646

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