ArticleArquivos de neuro-psiquiatria2024
Median nerve impairment in leprosy: how does it differ from the classic carpal tunnel syndrome?
Article in Arquivos de neuro-psiquiatria, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Diagnostic performance of peripheral nerve palpation compared with ultrasonography in leprosy neuropathy: A prospective real-world clinical evaluation.PLoS neglected tropical diseases · 2026Article
- Pure neural leprosy in a child: case report and diagnostic challenges.Revista da Sociedade Brasileira de Medicina Tropical · 2026Article
- Exploring the Neurological Manifestations of Leprosy: Clinical Insights and Implications.Cureus · 2025Review
- Neurophysiology combined with sonography as a useful tool in median nerve leprosy diagnosis.Arquivos de neuro-psiquiatria · 2024Article
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10 authors.
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Abstract
backgroundCarpal tunnel syndrome (CTS) has already been described as a possible form of neural leprosy presentation. However, the median nerve can be involved in this neuropathy in proximal segments and, sometimes, with an asymmetric impairment of the digital branches.
objectiveTo detail the pattern of median nerve impairment through nerve conduction study (NCS) and ultrasound evaluation.
methodsThis cross-sectional study comprises 15 primary neural leprosy (PNL) patients and 14 patients with CTS who underwent peripheral nerve ultrasonography and NCS evaluation.
resultsFrom the total, 92.8% of patients with CTS and 80% with PNL had bilateral impairment of the median nerve, with 27 nerves in each group. Considering the cross-sectional area (CSA) of the tunnel (Mt) segment, 63% of the nerves in the CTS and 74.1% in the PNL groups were found to be thickened, with an average CSA of 13.4 ± 4.4 and 12.4 ± 4.6, respectively (
conclusionThe presence of neural thickening and demyelinating impairment in the segments proximal to the carpal tunnel favors the diagnosis of leprosy.
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