Evidence map›Paper›PMID 39657965›Full record

ReviewHuman reproduction (Oxford, England)2025

Ethics of artificial intelligence in embryo assessment: mapping the terrain.

Julian J Koplin, Molly Johnston, Amy N S Webb, Andrea Whittaker, Catherine Mills

Abstract readReview
In one paragraph

Review in Human reproduction (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. From genes to germ layers: virtual twins of gastruloids.NPJ systems biology and applications · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Genetic and Epigenetic Risks of Male Infertility in ART.International journal of molecular sciences · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julian J KoplinMonash Bioethics Centre, Monash University, Clayton, VIC, Australia.ORCID 0000-0002-2752-7334
Molly JohnstonMonash Bioethics Centre, Monash University, Clayton, VIC, Australia.ORCID 0000-0002-3786-0843
Amy N S WebbMonash Bioethics Centre, Monash University, Clayton, VIC, Australia.
Andrea WhittakerSchool of Social Sciences, Monash University, Clayton, VIC, Australia.ORCID 0000-0002-2616-9651
Catherine MillsMonash Bioethics Centre, Monash University, Clayton, VIC, Australia.ORCID 0000-0003-1684-418X

Funding

Ferring Australia Human Reproduction Research Grant Scheme (2022)
6 · The paper itself

Abstract

Artificial intelligence (AI) has the potential to standardize and automate important aspects of fertility treatment, improving clinical outcomes. One promising application of AI in the fertility clinic is the use of machine learning (ML) tools to assess embryos for transfer. The successful clinical implementation of these tools in ways that do not erode consumer trust requires an awareness of the ethical issues that these technologies raise, and the development of strategies to manage any ethical concerns. However, to date, there has been little published literature on the ethics of using ML in embryo assessment. This mini-review contributes to this nascent area of discussion by surveying the key ethical concerns raised by ML technologies in healthcare and medicine more generally, and identifying which are germane to the use of ML in the assessment of embryos. We report concerns about the 'dehumanization' of human reproduction, algorithmic bias, responsibility, transparency and explainability, deskilling, and justice.

Indexed as

Artificial IntelligenceEmbryo TransferPreimplantation DiagnosisFemaleHumansMachine LearningPregnancyReproductive Techniques, AssistedAI transparencyartificial intelligencebioethicsembryo assessmentembryo selectionmachine learning

Identifiers

PMID39657965
PMCPMC11788194

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.