Evidence map›Paper›PMID 39657633›Full record

ReviewThe ISME journal2025

Emerging role of rare earth elements in biomolecular functions.

Wenyu Yang, Kaijuan Wu, Hao Chen, Jing Huang, Zheng Yu

Abstract readReview
In one paragraph

Review in The ISME journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenyu YangHuman Microbiome and Health Group, Department of Parasitology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China.
Kaijuan WuHuman Microbiome and Health Group, Department of Parasitology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China.
Hao ChenHuman Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China.
Jing HuangHuman Microbiome and Health Group, Department of Parasitology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China.
Zheng YuHuman Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China.

Funding

Innovation-Driven Research Programme of Central South University 2023CXQD059National Natural Science Foundation of China 32 170 071Natural Science Foundation of Hunan Province 2023JJ30651
6 · The paper itself

Abstract

The importance of rare earth elements is increasingly recognized due to the increased demand for their mining and separation. This demand is driving research on the biology of rare earth elements. Biomolecules associated with rare earth elements include rare earth element-dependent enzymes (methanol dehydrogenase XoxF, ethanol dehydrogenase ExaF/PedH), rare earth element-binding proteins, and the relevant metallophores. Traditional (chemical) separation methods for rare earth elements harvesting and separation are typically inefficient, while causing environmental problems, whereas bioharvesting, potentially, offers more efficient, more green platforms. Here, we review the current state of research on the biological functions of rare earth element-dependent biomolecules, and the characteristics of the relevant proteins, including the specific amino acids involved in rare earth metal binding. We also provide an outlook at strategies for further understanding of biological processes and the potential applications of rare earth element-dependent enzymes and other biomolecules.

Indexed as

Metals, Rare EarthProteinsMetals, Rare EarthProteinsethanol dehydrogenase ExaF/PedHlanmodulin (LanM)methanol dehydrogenase XoxFmethylotrophs and methanotrophsRare earth elements (REEs)

Identifiers

PMID39657633
PMCPMC11845868

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.