Evidence map›Paper›PMID 39657326›Full record

ArticlePhysics in medicine and biology2024

Investigation of hydrogen peroxide yields and oxygen consumption in high dose rate irradiation: a TOPAS-nBio Monte Carlo study.

Wook-Geun Shin, J Naoki D-Kondo, José Ramos-Méndez, Jay A LaVerne, Bethany Rothwell, Alejandro Bertolet, Aimee McNamara, Bruce Faddegon, Harald Paganetti, Jan Schuemann

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wook-Geun ShinPhysics Division, Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, United States of America.ORCID 0000-0002-8622-1888
J Naoki D-KondoDepartment of Radiation Oncology, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA 94115, United States of America.ORCID 0000-0002-4410-1925
José Ramos-MéndezDepartment of Radiation Oncology, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA 94115, United States of America.ORCID 0000-0002-8106-5142
Jay A LaVerneRadiation Laboratory and Department of Physics and Astronomy, University of Notre Dame, Notre Dame, IN 46556, United States of America.ORCID 0000-0002-8383-7476
Bethany RothwellPhysics Division, Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, United States of America.ORCID 0000-0002-3323-671X
Alejandro BertoletPhysics Division, Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, United States of America.ORCID 0000-0002-9890-693X
Aimee McNamaraRadformation Inc, 261 Madison Ave, 9th Floor, New York, NY 10017, United States of America.ORCID 0000-0001-8792-0464
Bruce FaddegonDepartment of Radiation Oncology, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA 94115, United States of America.ORCID 0000-0002-4573-1582
Harald PaganettiPhysics Division, Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, United States of America.ORCID 0000-0002-6257-2413
Jan SchuemannPhysics Division, Department of Radiation Oncology, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, United States of America.ORCID 0000-0002-7554-8818

Funding

TOPAS - nBio, a Monte Carlo tool for radiation biology researchR01CA187003 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SCHUEMANN, JAN PATRICK OSCAR · 2015 to 2024
$4.8M
Using experimentally-guided multi-scale modeling to determining the mechanism of FLASH tissue sparingR01CA266419 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SCHUEMANN, JAN PATRICK OSCAR · 2022 to 2025
$3.3M
Explore the therapeutic potential of small-molecule immune modulatorsR01CA226419 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI CHEN, CHUO · 2019 to 2023
$1.9M
Dose-Rate Variations for Patient Treatments in Flash and conventional radiation therapyR21CA252562 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SCHUEMANN, JAN PATRICK OSCAR · 2021 to 2022
$416k
NCI NIH HHS R01 CA187003NCI NIH HHS R01 CA226419NCI NIH HHS R01 CA266419NCI NIH HHS R21 CA252562
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hydrogen PeroxideMonte Carlo MethodRadiation DosageOxygen ConsumptionTemperatureHydrogen Peroxidedose ratehydrogen peroxide yieldsMonte Carlo simulationoxygen consumptionradiochemical yields

Identifiers

PMID39657326
PMCPMC12184618

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.