ArticleThe Journal of infectious diseases2025
Parvovirus B19 and Human Herpes Virus 6B and 7 Are Frequently Found DNA Viruses in the Human Thymus But Show No Definitive Link With Myasthenia Gravis.
Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Thymic function as a central determinant of immune competence and clinical outcomes.Seminars in immunopathology · 2026Review
- Possible involvement of viral infection in the pathogenesis of myasthenia gravis.Journal of neurovirology · 2026Review
- Thymic hyperplasia in myasthenia gravis: a narrative review.Mediastinum (Hong Kong, China) · 2025Review
- Thymus research in relation to myasthenia gravis: a new perspective on cell subpopulations and future directions.Frontiers in immunology · 2025Review
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Authors and funding
20 authors.
Funding
Abstract
Myasthenia gravis (MG) is a rare autoimmune disorder characterized by muscle weakness resulting from autoantibody-mediated disruption of the neuromuscular junction. Notably, it is also frequently associated with thymic pathology. This study explores the relationship between MG and DNA viruses in the thymus, employing targeted next-generation sequencing and quantitative polymerase chain reaction to analyze thymic tissue samples from both patients with MG and healthy controls. We detected human herpes virus 6B and 7, Epstein-Barr virus, and parvovirus B19 (B19V) across various tissue groups. However, no significant enrichment of these viruses was observed in the thymic tissue of patients with MG.
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