Evidence map›Paper›PMID 39656957›Full record

SynthesisDento maxillo facial radiology2025

Detection of periodontal bone loss and periodontitis from 2D dental radiographs via machine learning and deep learning: systematic review employing APPRAISE-AI and meta-analysis.

Yahia H Khubrani, David Thomas, Paddy J Slator, Richard D White, Damian J J Farnell

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Dento maxillo facial radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yahia H KhubraniSchool of Dentistry, Cardiff University, The Annexe, University Dental Hospital, Heath Park, Cardiff CF14 4XY, United Kingdom.ORCID 0009-0002-2619-8046
David ThomasSchool of Dentistry, Cardiff University, The Annexe, University Dental Hospital, Heath Park, Cardiff CF14 4XY, United Kingdom.ORCID 0000-0001-7319-5820
Paddy J SlatorSchool of Computer Science and Informatics, Cardiff University, Cardiff CF24 4AG, United Kingdom.ORCID 0000-0001-6967-989X
Richard D WhiteDepartment of Clinical Radiology, University Hospital of Wales, Cardiff CF14 4XW, United Kingdom.ORCID 0000-0002-2370-4575
Damian J J FarnellSchool of Dentistry, Cardiff University, The Annexe, University Dental Hospital, Heath Park, Cardiff CF14 4XY, United Kingdom.ORCID 0000-0003-0662-1927

Funding

Jazan UniversitySaudi Arabia Cultural Bureau
6 · The paper itself

Abstract

objectivesPeriodontitis is a serious periodontal infection that damages the soft tissues and bone around teeth and is linked to systemic conditions. Accurate diagnosis and staging, complemented by radiographic evaluation, are vital. This systematic review (PROSPERO ID: CRD42023480552) explores artificial intelligence (AI) applications in assessing alveolar bone loss and periodontitis on dental panoramic and periapical radiographs.

methodsFive databases (Medline, Embase, Scopus, Web of Science, and Cochrane's Library) were searched from January 1990 to January 2024. Keywords related to "artificial intelligence", "Periodontal bone loss/Periodontitis", and "Dental radiographs" were used. Risk of bias and quality assessment of included papers were performed according to the APPRAISE-AI Tool for Quantitative Evaluation of AI Studies for Clinical Decision Support. Meta analysis was carried out via the "metaprop" command in R V3.6.1.

resultsThirty articles were included in the review, where 10 papers were eligible for meta-analysis. Based on quality scores from the APPRAISE-AI critical appraisal tool of the 30 papers, 1 (3.3%) were of very low quality (score < 40), 3 (10.0%) were of low quality (40 ≤ score < 50), 19 (63.3%) were of intermediate quality (50 ≤ score < 60), and 7 (23.3%) were of high quality (60 ≤ score < 80). No papers were of very high quality (score ≥ 80). Meta-analysis indicated that model performance was generally good, eg, sensitivity 87% (95% CI, 80%-93%), specificity 76% (95% CI, 69%-81%), and accuracy 84% (95% CI, 75%-91%).

conclusionDeep learning shows much promise in evaluating periodontal bone levels, although there was some variation in performance. AI studies can lack transparency and reporting standards could be improved. Our systematic review critically assesses the application of deep learning models in detecting alveolar bone loss on dental radiographs using the APPRAISE-AI tool, highlighting their efficacy and identifying areas for improvement, thus advancing the practice of clinical radiology.

Indexed as

Alveolar Bone LossDeep LearningMachine LearningPeriodontitisRadiography, DentalRadiography, Dental, DigitalHumansRadiography, Panoramicartificial intelligencedeep learningpanoramic radiographsperiapical radiographsperiodontitis

Identifiers

PMID39656957
PMCPMC11979759

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.