ArticleJournal of the Pediatric Infectious Diseases Society2025
Infections and Antibiotic Resistance in Malawian Children Under Five-Years Old Hospitalized With Severe Acute Malnutrition.
Bryan J Vonasek, Mwawi Nyirongo, Alexander Kondwani, Tiwonge Kamvaunamwali, Doris Ng'oma, Emily J Ciccone, James Kaphatika, Amazing-Grace Tepeka, Mercy Kumwenda, Jens Eickhoff and 2 more
Abstract read
In one paragraphArticle in Journal of the Pediatric Infectious Diseases Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
12 authors.
Bryan J VonasekDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-5657-0980 Mwawi NyirongoDepartment of Paediatrics and Child Health, Kamuzu Central Hospital, Lilongwe, Malawi.
Alexander KondwaniDepartment of Paediatrics and Child Health, Kamuzu Central Hospital, Lilongwe, Malawi.
Tiwonge KamvaunamwaliUNC Project Malawi, Lilongwe, Malawi.
Doris Ng'omaUNC Project Malawi, Lilongwe, Malawi.
Emily J CicconeDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0003-2445-8473 James KaphatikaUNC Project Malawi, Lilongwe, Malawi.
Amazing-Grace TepekaUNC Project Malawi, Lilongwe, Malawi.
Mercy KumwendaDepartment of Paediatrics and Child Health, Kamuzu Central Hospital, Lilongwe, Malawi.
Jens EickhoffDepartment of Biostatistics & Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Anthony J Garcia-PratsDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Tisungane MvaloUNC Project Malawi, Lilongwe, Malawi.
Funding
UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8MMicrobial Pathogenesis &Host Responses Training ProgramT32AI055397 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 2003 to 2024
$5.5MLeveraging Molecular Technologies to Improve Diagnosis and Management of Pediatric Acute Respiratory Illness in Resource-Constrained SettingsK23AI173658 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Emily Jane Ciccone · 2023 to 2026
$878kFIC NIH HHS D43 TW009340NIAID NIH HHS K23 AI173658NIAID NIH HHS L40 AI178767NIAID NIH HHS T32 AI055397
6 · The paper itselfAbstract
This prospective cohort study from Malawi updates our understanding of the burden of bacterial infections and drug resistance in children <5 years hospitalized with severe acute malnutrition. Urinary tract infection was diagnosed in 20% and bacteremia in 10%. Resistance to first- and second-line antibiotics occurred in >1/3 of the bacteria isolated.
Indexed as
Anti-Bacterial AgentsBacterial InfectionsDrug Resistance, BacterialSevere Acute MalnutritionBacteremiaChild, PreschoolFemaleHospitalizationHumansInfantMalawiMaleProspective StudiesUrinary Tract InfectionsAnti-Bacterial AgentsMalawiserious bacterial infectionssevere acute malnutrition
Identifiers
PMID39656758
PMCPMC12187324
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