Evidence map›Paper›PMID 39656600›Full record

Trial reportCancer science2025

Phase II study of perioperative camrelizumab and XELOX for locally advanced gastric or gastroesophageal junction adenocarcinoma.

Jiaxing He, Bo Zhang, Shuai Zhou, Ying Yang, Zhuo Han, Tao Wu, Qing Qiao, Haicheng Yang, Xianli He, Nan Wang

Registry-linked trialAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Cancer science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05715632 (Prospective, Single Arm, Single Center Exploratory Study on the New Adjuvant Therapy of Camrelizumab Combined With XELOX Regimen for Locally Advanced Gastric Cancer), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05715632 naunknown statusnot on this map

Prospective, Single Arm, Single Center Exploratory Study on the New Adjuvant Therapy of Camrelizumab Combined With XELOX Regimen for Locally Advanced Gastric Cancer

TypeinterventionalSponsorTang-Du HospitalRan2023 to 2025Enrolled46ConditionsGastric CancerArmsCarrelizumab combined with XELOX
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiaxing HeDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Bo ZhangDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Shuai ZhouDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Ying YangDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Zhuo HanDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Tao WuDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Qing QiaoDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Haicheng YangDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Xianli HeDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.
Nan WangDepartment of General Surgery, Air Force Medical University Tangdu Hospital, Xi'an, China.ORCID https://orcid.org/0000-0002-6576-6096

Funding

National Natural Science Foundation of China 82273375Superintendent of Innovation Capability Support Program of Shaanxi 2024RS-CXTD-82Treatment Innovation Capability Enhancement Project of Tangdu Hospital 2022TDLCTS14
6 · The paper itself

Abstract

Immune checkpoint inhibitors combined with chemotherapy have shown promising efficacy in treating gastric or gastroesophageal junction (G/GEJ) adenocarcinoma in the neoadjuvant setting. This phase II trial (NCT05715632) aimed to investigate the efficacy and safety of perioperative camrelizumab plus XELOX in patients with locally advanced G/GEJ adenocarcinoma. Treatment-naive patients with cT3-4aN1-3 M0 resectable locally advanced G/GEJ adenocarcinoma were recruited to receive camrelizumab (200 mg, intravenously) on Day 1 combined with XELOX (oxaliplatin at 130 mg/m

Indexed as

AdenocarcinomaAntibodies, Monoclonal, HumanizedAntineoplastic Combined Chemotherapy ProtocolsCapecitabineEsophageal NeoplasmsEsophagogastric JunctionStomach NeoplasmsAdultAgedFemaleHumansMaleMiddle AgedNeoadjuvant TherapyOxaloacetatesAntibodies, Monoclonal, HumanizedcamrelizumabCapecitabineOxaloacetatescamrelizumabgastric cancergastroesophageal junction adenocarcinomaperioperative treatmentphase II study

Identifiers

PMID39656600
PMCPMC11875781

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.