Evidence map›Paper›PMID 39656384›Full record

ArticleInternational journal of clinical pharmacy2025

Pharmacist-led new medicine service: a real-world cohort study in the Netherlands on drug-related problems, satisfaction, and self-efficacy in cardiovascular patients transitioning to primary care.

Hendrik T Ensing, Nelly Kurt, Ruby A Janssen, Ellen S Koster, Eibert R Heerdink

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Article in International journal of clinical pharmacy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hendrik T EnsingOutpatient Pharmacy 'de Brug 24/7', Zorggroep Almere, Almere, The Netherlands.
Nelly KurtDepartment of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, PO Box 80082, 3508 TB, Utrecht, The Netherlands.
Ruby A JanssenInstitute of Paramedic Studies, HU University of Applied Sciences, Utrecht, The Netherlands.
Ellen S KosterCenter of Education, Clinical Health Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
Eibert R HeerdinkDepartment of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, PO Box 80082, 3508 TB, Utrecht, The Netherlands. e.r.heerdink@uu.nl.ORCID http://orcid.org/0000-0002-5946-7209

Funding

ZonMw 848024021
6 · The paper itself

Abstract

backgroundPatients transitioning from hospital to home while starting long-term cardiovascular medicines are likely to experience drug-related problems (DRPs). The New Medicine Service (NMS) may support readmission to primary care.

aimTo evaluate NMS in a real world setting, for patients transitioning from hospital to primary care with newly prescribed cardiovascular medicines on identifying DRPs, patient satisfaction with medication information and patient self-efficacy. Secondary objectives were identifying risk factors for DRPs and assessing first-fill discontinuation.

methodA cohort study in an outpatient pharmacy and 14 community pharmacies in Almere, the Netherlands, involved patients ≥ 18 years receiving new cardiovascular prescriptions. Usual pharmacy care was complemented with a telephone counselling two weeks post-dispensing to identify and address DRPs. Patient satisfaction and self-efficacy were assessed during a follow-up call. First-fill discontinuation was measured using dispensing data, and logistic regression identified risk factors for DRPs.

resultsOf 1647 eligible patients, 743 received NMS; 72.5% experienced ≥ 1 DRP. NMS improved patients' satisfaction with information and self-efficacy (p < 0.001). Outpatient visits (adj. OR 0.64), cardiovascular medicine use (adj. OR 0.65), and use of chronic medicines (adj. OR 1.71) influenced DRPs. First-fill discontinuation remained unchanged post-NMS, but patients with DRPs discontinued more often (14.8% vs. 8.6%, p = 0.030).

conclusionImplementing the NMS in a real-world transitional care setting allowed pharmacists to identify DRPs and provide counselling tailored to patient needs. Patients reported higher satisfaction with information and increased self-efficacy. Priority should be given to at-risk patients for DRPs, and deploy other pharmacy staff to perform the NMS.

Indexed as

Cardiovascular AgentsCardiovascular DiseasesCommunity Pharmacy ServicesDrug-Related Side Effects and Adverse ReactionsPatient SatisfactionPharmacistsPrimary Health CareSelf EfficacyAdultAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedCardiovascular AgentsCommunity pharmacistDrug-related problemsMedication counsellingMedication initiationPrimary careTransitional care

Identifiers

PMID39656384
PMCPMC11920310

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