Evidence map›Paper›PMID 39656302›Full record

ArticleInternational ophthalmology2024

In vivo confocal microscopy findings about ocular surface recovery in patients following pterygium excision combined with conjunctival autograft.

Mi Xu, YunZhi Shen, ZhengWei Zhang, HongJuan Sun, Song Sun

Abstract read
In one paragraph

Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mi XuDepartment of Ophthalmology, Jiangnan University Medical Center, Wuxi No.2 People's Hospital, Affiliated Wuxi Clinical College of Nantong University, Wuxi, 214000, People's Republic of China.
YunZhi ShenDepartment of Ophthalmology, Wuxi Aier Eye Hospital Co., Wuxi, 214000, People's Republic of China.
ZhengWei ZhangDepartment of Ophthalmology, Jiangnan University Medical Center, Wuxi No.2 People's Hospital, Affiliated Wuxi Clinical College of Nantong University, Wuxi, 214000, People's Republic of China.
HongJuan SunDepartment of Ophthalmology, Jiangnan University Medical Center, Wuxi No.2 People's Hospital, Affiliated Wuxi Clinical College of Nantong University, Wuxi, 214000, People's Republic of China.
Song SunDepartment of Ophthalmology, Jiangnan University Medical Center, Wuxi No.2 People's Hospital, Affiliated Wuxi Clinical College of Nantong University, Wuxi, 214000, People's Republic of China. sxuefeng@vip.sina.com.

Funding

the Elderly Health Research Project of Jiangsu Province No. 2022043the Research Project of Wuxi Commission of Health No. M202131the Social Development Project of Jiangsu Provincial Department of Science and Technology No. BE2022699Top Talent Support Program for young and middle-aged people of Wuxi Health Committee No. HB2020030
6 · The paper itself

Abstract

purposeTo study cellular and neural changes around the donor and recipient areas after pterygium excision combined with autologous conjunctival transplantation using corneal confocal microscopy, we evaluated the postoperative impact of this surgical procedure.

methodsPatients with primary pterygium located on the nasal side who visited the Department of Ophthalmology of Wuxi Second People's Hospital between April and August 2023 were enrolled. Age-matched healthy eyes were included as the control group. IVCM was performed in the affected eyes, 6 months after pterygium excision. The images of the central conjunctival cells in the recipient and donor areas, the cells of each layer of the cornea around the recipient and donor area (around 2 mm from the nasal and upper corneal margins), and the structures of the corneal margins were recorded in the affected eyes and statistically compared with the corresponding areas in the control eyes.

resultsSeventeen eyes of 14 patients with primary pterygium located on the nasal side (mean 64 ± 8.74 years old), and 17 eyes of nine patients as age-matched normal controls were included. Compared with those of normal eyes, the density of corneal pterygoid epithelium around the recipient area (5104 ± 599 cells/mm

conclusionsPterygium excision combined with autologous conjunctival transplantation with corneal stem cells can better promote the repair of most corneal cells around the recipient area and fence-like structures of the corneal rim 6 months postoperatively, but there may be some damage to the corneal conjunctival structures around the donor area.

Indexed as

ConjunctivaMicroscopy, ConfocalPterygiumTransplantation, AutologousAgedAutograftsCorneaEpithelium, CornealFemaleFollow-Up StudiesHumansMaleMiddle AgedOphthalmologic Surgical ProceduresConjunctivaCorneaIn vivo confocal microscopeLimbusOcular surfacePterygium

Identifiers

PMID39656302
PMCPMC11632030

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.