Gastrointestinal quality of life in children born with gastroschisis.

Matilda Bräutigam, Michaela Dellenmark-Blom, Kate Abrahamsson, Cathrine Gatzinsky, Vladimir Gatzinsky

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Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Matilda BräutigamDepartment of Pediatric Surgery, Queen Silvia Children's Hospital, Sahlgrenska University, Hospital, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, 416 85, Gothenburg, Sweden. matilda.brautigam@gu.se.

Michaela Dellenmark-BlomDepartment of Pediatric Surgery, Queen Silvia Children's Hospital, Sahlgrenska University, Hospital, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, 416 85, Gothenburg, Sweden.

Kate AbrahamssonDepartment of Pediatric Surgery, Queen Silvia Children's Hospital, Sahlgrenska University, Hospital, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, 416 85, Gothenburg, Sweden.

Cathrine GatzinskyDepartment of Pediatric Surgery, Queen Silvia Children's Hospital, Sahlgrenska University, Hospital, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, 416 85, Gothenburg, Sweden.

Vladimir GatzinskyDepartment of Pediatric Surgery, Queen Silvia Children's Hospital, Sahlgrenska University, Hospital, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, 416 85, Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim was to determine gastrointestinal (GI)-related QoL in children born with gastroschisis (GS).

methodsTotally, 58/83 families of children (aged 2-18 years) operated for GS at a tertiary pediatric surgical center accepted participation. Children aged 5-18 and one parent (child aged 2-18) completed the Swedish version of the PedsQL™ gastrointestinal symptoms module, evaluating GI-related QoL with 14 different GI-specific scales, norm values for Hirschsprung's disease (HD), esophageal atresia (EA), and functional constipation (FC) that were used for comparison.

resultsChildren with GS had significantly lower parent-reported scores on "Gas and bloating" compared with children with EA (77.0 vs 85.5, p = 0.039). In the child report and in the parent report, scores on several GI scales were like those of children with EA. Parents of children with GS had higher scores for 8/14 scales compared to HD and higher scores for 12/14 scales compared to FC. Clinical GS-specific factors for worse GI-QoL were identified, including "Days in ventilator" and "Days with Silo and Patch".

conclusionsGS has an impact on GI-related QoL, comparable to that in EA, but not to HD or FC. The GS-specific factors of worse QoL show the importance regarding a GS follow-up program including considering clinical factors.

Indexed as

GastroschisisQuality of LifeAdolescentChildChild, PreschoolEsophageal AtresiaFemaleHumansMaleSurveys and QuestionnairesSwedenGastrointestinal quality of lifeGastroschisisPedsQL gastrointestinal symptom moduleQuality of lifeSilo

Identifiers

PMID39656298

DOI10.1016/j.earlhumdev.2019.104936

PMCPMC11632061

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.