Evidence map›Paper›PMID 39656188›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025

Impact of Clinician Feedback Reports on Antibiotic Use in Children Hospitalized With Community-acquired Pneumonia.

Kathleen Chiotos, Lauren Dutcher, Robert W Grundmeier, Didien Meyahnwi, Ebbing Lautenbach, Melinda M Neuhauser, Lauri A Hicks, Keith W Hamilton, Yun Li, Julia E Szymczak and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06027593 (Using Electronically Derived AutoMated RePOrts of Appropriate Antibiotic Use to Inform SteWardship IntERventions), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06027593 nacompletednot on this map

Using Electronically Derived AutoMated RePOrts of Appropriate Antibiotic Use to Inform SteWardship IntERventions

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2022 to 2024Enrolled26,139ConditionsCommunity-acquired Pneumonia, Acute Otitis Media, PharyngitisArmsQuasi experimental intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kathleen ChiotosDivision of Critical Care Medicine, Department of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-0204-8708
Lauren DutcherDivision of Infectious Diseases, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-5011-7950
Robert W GrundmeierDepartment of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Didien MeyahnwiClinical Futures, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Ebbing LautenbachDivision of Infectious Diseases, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Melinda M NeuhauserDivision of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Lauri A HicksDivision of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0002-2383-9357
Keith W HamiltonDivision of Infectious Diseases, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Yun LiDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Julia E SzymczakDivision of Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah, USA.ORCID 0000-0002-3230-8670
Brandi M MullerDivision of Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Morgan CongdonDepartment of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-8528-0480
Emily KaneDepartment of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Jessica HartDivision of General Pediatrics, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Levon UtidjianDepartment of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-2189-108X
Leigh CressmanCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Anne Jaskowiak-BarrCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jeffrey S GerberDivision of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3076-3186

Funding

Intramural CDC HHS CC999999Safety and Healthcare Epidemiology Prevention Research DevelopmentU.S. Centers for Disease Control and Prevention
6 · The paper itself

Abstract

backgroundFeedback reports summarizing clinician performance are effective tools for improving antibiotic use in the ambulatory setting, but the effectiveness of feedback reports in the hospital setting is unknown.

methodsQuasi-experimental study conducted between December 2021 and November 2023 within a pediatric health system measuring the impact of clinician feedback reports delivered by email and reviewed in a monthly meeting on appropriate antibiotic use in children hospitalized with community-acquired pneumonia (CAP). We used an interrupted time series analysis (ITSA) to estimate the immediate change and change over time in the proportion of CAP encounters adherent to validated metrics of antibiotic choice and duration, then used Poisson regression to estimate intervention effect as a risk ratio (RR).

resultsPreintervention, 213 of 413 (52%) encounters received the appropriate antibiotic choice and duration, which increased to 308 of 387 (80%) postintervention. The ITSA demonstrated an immediate 18% increase in the proportion of CAP encounters receiving both the appropriate antibiotic choice and duration (95% confidence interval [CI]: 3-33%), with no further change over time (-0.3% per month, 95% CI: -2%-2%). In the Poisson model adjusted for age, sex, race, season, site, and intensive care unit admission, the intervention was associated with a 32% increase in the rate of appropriate antibiotic choice and duration (RR 1.32, 95% CI: 1.12-1.56, P < .01). No difference in length of stay or revisits were detected postintervention.

conclusionsThe intervention was associated with an increase in clinician adherence to antibiotic choice and duration recommendations for children hospitalized with CAP.

Indexed as

Anti-Bacterial AgentsCommunity-Acquired InfectionsFeedbackPneumoniaPractice Patterns, Physicians'AdolescentChildChild, PreschoolCommunity-Acquired PneumoniaFemaleHospitalizationHumansInfantInterrupted Time Series AnalysisMaleAnti-Bacterial Agentsantibioticantimicrobial stewardshipaudit and feedbackcommunity-acquired pneumoniafeedback report

Identifiers

PMID39656188
PMCPMC12120840

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.