Evidence map›Paper›PMID 39655481›Full record

ArticleJournal of primary care & community health

Member Adherence to a Health Insurer-Sponsored Gap Closure Program Using Multi-Target Stool DNA Test for Colorectal Cancer Screening.

Mallik Greene, Timo Pew, Quang Le, Alisdair Philp, William K Johnson, A Burak Ozbay, John Kisiel, Michael Dore, Derek Ebner, A Mark Fendrick and 1 more

Abstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mallik GreeneExact Sciences Corporation, Madison, WI, USA.ORCID 0000-0001-9363-5483
Timo PewExact Sciences Corporation, Madison, WI, USA.
Quang LeExact Sciences Corporation, Madison, WI, USA.
Alisdair PhilpExact Sciences Corporation, Madison, WI, USA.
William K JohnsonExact Sciences Corporation, Madison, WI, USA.
A Burak OzbayExact Sciences Corporation, Madison, WI, USA.
John KisielMayo Clinic, Rochester, MN, USA.
Michael DoreDuke University, Durham, NC, USA.
Derek EbnerMayo Clinic, Rochester, MN, USA.
A Mark FendrickUniversity of Michigan, Ann Arbor, MI, USA.
Paul LimburgExact Sciences Corporation, Madison, WI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe member adherence to a mail-based, health insurer-sponsored gap closure program for colorectal cancer (CRC) screening using multi-target stool DNA (mt-sDNA; Cologuard

methodsCombined patient data from Exact Sciences Laboratories LLC and data from mass-mailed mt-sDNA orders placed by a large Medicare Advantage Insurance Plan were analyzed (03/01/2023-06/30/2023). Adherence and time to test return were the primary and secondary outcomes, respectively. Their association with patient characteristics was evaluated using multivariable regression.

resultsAmong the 3201 member-patients included (86.6% aged 65-75 years; 58.7% female), adherence rate was 49.4%, and mean time to test return was 25.5 days. After multivariable adjustment, the odds of test return were significantly higher among 65- to 75-year-olds (odds ratio [OR] = 1.59 relative to 45- to 64-year-olds), those living in small towns (OR = 1.43 relative to metropolitan-located individuals), and with digital outreach via both SMS and email (OR = 4.31 relative to no digital outreach). Time to test return was shorter in 65- to 75-year-olds than in 45- to 64-year-olds and was not associated with other patient characteristics.

conclusionsMass-mailed mt-sDNA tests for CRC screening were associated with an overall adherence rate of about 50% in this Medicare Advantage population, with higher likelihood of test return among patients receiving digital outreach.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerFecesAgedFemaleHumansMaleMedicare Part CMiddle AgedPatient ComplianceUnited Statescologuardcolorectal cancer screeningcolorectal neoplasmsinsuranceMedicare Advantagemt-sDNA

Identifiers

PMID39655481
PMCPMC11629422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.