ArticleWiley interdisciplinary reviews. Computational statistics
Neuroimaging statistical approaches for determining neural correlates of Alzheimer's disease via positron emission tomography imaging.
Article in Wiley interdisciplinary reviews. Computational statistics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The functional foetal brain: A systematic review and meta-analysis.Developmental cognitive neuroscience · 2026Pooled it
- Assessing subcortical, brainstem and cerebellar metabolic patterns using [18F]FDG PET-CT imaging in dementia with Lewy bodies.European journal of nuclear medicine and molecular imaging · 2026Article
- Assessing the metabolism of the olfactory circuit by use ofAlzheimer's research & therapy · 2024Article
- Using zero-inflated and hurdle regression models to analyze schistosomiasis data of school children in the southern areas of Ghana.PloS one · 2024Article
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Authors and funding
5 authors.
Funding
Abstract
Alzheimer's disease (AD) is a degenerative disorder involving significant memory loss and other cognitive deficits, manifesting as a progression from normal cognitive functioning to mild cognitive impairment to AD. The sooner an accurate diagnosis of probable AD is made, the easier it is to manage symptoms and plan for future therapy. Functional neuroimaging stands to be a useful tool in achieving early diagnosis. Among the many neuroimaging modalities, positron emission tomography (PET) provides direct regional assessment of, among others, brain metabolism, cerebral blood flow, amyloid deposition-all quantities of interest in the characterization of AD. However, there are analytic challenges in identifying early indicators of AD from these high-dimensional imaging data sets, and it is unclear whether early indicators of AD are more likely to emerge in localized patterns of brain activity or in patterns of correlation between distinct brain regions. Early PET-based analyses of AD focused on alterations in
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Registered trials
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