Evidence map›Paper›PMID 39655169›Full record

ArticleERJ open research2024

Childhood lung function is associated with adolescent-onset and persistent asthma.

Hans Jacob L Koefoed, Anhar Ullah, Jenny Hallberg, Simon Kebede Merid, Maura M Kere, Lesley Lowe, Angela Simpson, Clare S Murray, Ulrike Gehring, Roel Vermeulen and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hans Jacob L KoefoedUniversity of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Pulmonology and Pediatric Allergology, Groningen, the Netherlands.ORCID https://orcid.org/0000-0002-8285-0492
Anhar UllahNational Heart and Lung Institute, Imperial College London, London, UK.
Jenny HallbergKarolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden.
Simon Kebede MeridKarolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden.
Maura M KereKarolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-5725-2773
Lesley LoweDivision of Immunology, Immunity to infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Angela SimpsonDivision of Immunology, Immunity to infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Clare S MurrayDivision of Immunology, Immunity to infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Ulrike GehringInstitute of Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-3612-5780
Roel VermeulenInstitute of Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Inger KullKarolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden.
Anna BergströmKarolinska Institutet, Institute of Environmental Medicine, Stockholm, Sweden.
Judith M VonkUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-7531-4547
Adnan CustovicNational Heart and Lung Institute, Imperial College London, London, UK.
Erik MelénKarolinska Institutet, Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-8248-0663
Gerard H KoppelmanUniversity of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Pulmonology and Pediatric Allergology, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-8567-3252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Asthma is associated with impaired lung function; however, it is uncertain if a lower childhood lung function is associated with asthma onset and persistence during adolescence. The aims of the present study were to investigate the association between childhood lung function and onset and persistence of asthma during adolescence. Methods: In the population-based BAMSE (Sweden), PIAMA (Netherlands) and MAAS (UK) birth cohorts, we analysed the association of forced expiratory volume in 1 s (FEV Results: In the BAMSE, PIAMA and MAAS cohorts, asthma incidence in adolescence was 6.1% (112/1824), 3.4% (36/1050) and 5.0% (39/779), respectively. Persistent asthma from childhood to adolescence was observed in 8.2%, 6.4% and 7.7% of all subjects within the respective cohorts. A higher FEV Conclusions: A higher lung function at school age was associated with a lower risk of adolescent-onset asthma, predominantly in males. This indicates that a lower lung function in childhood may precede and or potentially contribute to asthma incidence and persistence.

Identifiers

PMID39655169
PMCPMC11626625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.