Evidence map›Paper›PMID 39655028›Full record

ArticleJournal of clinical and translational science2024

Examining the impact of the QUARTET USA trial using the translational science benefits model.

Guhan Iyer, Danielle Lazar, Abigail S Baldridge, Jairo Mejia, Clara K Chow, Namratha R Kandula, Olutobi A Sanuade, Linda Rosul, Jody D Ciolino, Mark D Huffman

Abstract read
In one paragraph

Article in Journal of clinical and translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guhan IyerCardiovascular Division and Global Health Center, Washington University in St. Louis., St. Louis. MO, USA.
Danielle LazarAccess Community Health Network, Chicago, IL, USA.
Abigail S BaldridgeDepartment of Preventive Medicine, Northwestern Feinberg School of Medicine, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-1573-0554
Jairo MejiaAccess Community Health Network, Chicago, IL, USA.
Clara K ChowWestmead Applied Research Center, University of Sydney, Sydney, Australia.
Namratha R KandulaDepartment of Medicine, Division of General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Olutobi A SanuadeDepartment of Population Health Sciences, Division of Health System Innovation and Research, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, UT, USA.
Linda RosulAccess Community Health Network, Chicago, IL, USA.
Jody D CiolinoDepartment of Preventive Medicine, Northwestern Feinberg School of Medicine, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-9060-5657
Mark D HuffmanCardiovascular Division and Global Health Center, Washington University in St. Louis., St. Louis. MO, USA.ORCID https://orcid.org/0000-0001-7412-2519

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MILDA Renne SAUNDERS · 2011 to 2026
$10.0M
NCATS NIH HHS UL1 TR002345NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

Evaluation of benefits beyond quantitative academic outputs is essential in determining translational research value. We used the Translational Science Benefits Model (TSBM) to examine the impact of the QUARTET USA trial using 30 benefits across 4 domains: Clinical, Community, Economic, and Policy. We found that the QUARTET USA trial demonstrated impact in six areas within the Clinical, and Community domains and had potential impact in two additional areas within the Community and Economic domains. Use of the TSBM supports the value of the QUARTET USA trial, which can be used as a template for future cardiovascular trials.

Indexed as

hypertensionrandomized trialResearch impacttranslational science

Identifiers

PMID39655028
PMCPMC11626589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.