Evidence map›Paper›PMID 39654909›Full record

ReviewBrain & spine2024

The concepts of Intra Spinal Pressure (ISP), Intra Thecal Pressure (ITP), and Spinal Cord Perfusion Pressure (SCPP) in acute, severe traumatic spinal cord injury: Narrative review.

Samira Saadoun, Hasan Asif, Marios C Papadopoulos

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain & spine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04936620 (Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04936620 narecruitingnot on this map

Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling

TypeinterventionalSponsorSt George's, University of LondonRan2021 to 2028Enrolled222ConditionsSpinal Cord InjuriesArmsDuroplasty, Spinal surgery
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Samira SaadounAcademic Neurosurgery Unit, Neuroscience and Cell Biology Research Institute, St. George's, University of London, Cranmer Terrace, Tooting, London, SW17 0RE, UK.
Hasan AsifAcademic Neurosurgery Unit, Neuroscience and Cell Biology Research Institute, St. George's, University of London, Cranmer Terrace, Tooting, London, SW17 0RE, UK.
Marios C PapadopoulosAcademic Neurosurgery Unit, Neuroscience and Cell Biology Research Institute, St. George's, University of London, Cranmer Terrace, Tooting, London, SW17 0RE, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is increasing interest in monitoring pressure from the injured spinal cord to guide the management of patients with acute, severe traumatic spinal cord injuries (TSCI). This is analogous to monitoring intracranial pressure and cerebral perfusion pressure in traumatic brain injury (TBI). Here, we explore key concepts in this field and novel therapies that are emerging from these ideas. We argue that the Monro-Kellie doctrine, a fundamental principle in TBI, may also apply to TSCI as follows: The injured cord swells, initially displacing surrounding cerebrospinal fluid (CSF) that prevents a rise in spinal cord pressure; once the CSF space is exhausted, the spinal cord pressure at the injury site rises. The spinal Monro-Kellie doctrine allows us to define novel concepts to guide the management of TSCI based on principles employed in the management of TBI such as intraspinal pressure (ISP), intrathecal pressure (ITP), spinal cord perfusion pressure (SCPP), spinal pressure reactivity index (sPRx), and optimum SCPP (SCPP

Indexed as

Critical care unitIschemiaMonitoringPerfusionProbeSpinal cord injury

Identifiers

PMID39654909
PMCPMC11626061

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.