Evidence map›Paper›PMID 39654503›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Coaxial Helices in Chiral Supramolecular Aggregates from Highly Hindered Chiral Allenes.

María Lago-Silva, Manuel Fernández-Míguez, Zulema Fernández, María Magdalena Cid, Emilio Quiñoá, Rafael Rodríguez, Félix Freire

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Lago-SilvaCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, E-15782, Santiago de Compostela, Spain.
Manuel Fernández-MíguezCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, E-15782, Santiago de Compostela, Spain.
Zulema FernándezCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, E-15782, Santiago de Compostela, Spain.
María Magdalena CidDepartamento de Química Orgánica, Universidade de Santiago de Compostela, E-15782, Santiago de Compostela, Spain.
Emilio QuiñoáCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, E-15782, Santiago de Compostela, Spain.
Rafael RodríguezCINBIO and Departamento de Química Orgánica, Campus Lagoas-Marcosende, Universidade de Vigo, Vigo, E-36310, Spain.
Félix FreireCINBIO and Departamento de Química Orgánica, Campus Lagoas-Marcosende, Universidade de Vigo, Vigo, E-36310, Spain.ORCID https://orcid.org/0000-0002-2672-5830

Funding

Agencia Estatal de Investigación PID2021-128057NB-I00Agencia Estatal de Investigación PID2022-136848NB-I00Agencia Estatal de Investigación RYC2022-035587-IEuropean Regional Development FundSecretaria Xeral de Investigación e Desenvolvemento, Xunta de Galicia ED431C 2022/21Xunta de Galicia ED431G 2019/03
6 · The paper itself

Abstract

Chiral allenes self-assembly following a cooperative mechanism into a supramolecular chiral aggregate consisting of two coaxial helices: the internal helix described by the allene stack and the external helix which consist in a 4-helix described by the four allene substituents. More precisely, this supramolecular aggregate possesses six axially chiral elements within its structure-the allene, the allene stack (internal helix) and the stacks of the four allene substituents (external 4-helix)-. Interestingly, slight variations in the magnitude of the tilting degree while keeping its P- or M- orientation (internal helix) can vary the orientation of the 4-axial motifs at the external helix. Thus, while (P)-1 produces a supramolecular helix with a Θ ca. 15° (P

Indexed as

AllenesAxial ChiralityChiral AggregatesHelixSupramolecular Polymers

Identifiers

PMID39654503
PMCPMC11878346

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.