Evidence map›Paper›PMID 39654485›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2025

Association Between Blood Pressure Variation During Dialysis and Cardio-Cerebrovascular Events.

Zhenliang Fan, Rujia Ye, Qiaorui Yang, Mengfan Yang, Riping Yin, Dongxue Zhao, Junfen Fan, Hongzhen Ma, Yiwei Shen, Hong Xia and 2 more

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhenliang FanNephrology Department, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.ORCID 0000-0002-3508-6954
Rujia YeNephrology Department, Yueqing Hospital of Traditional Chinese Medicine, Yueqing, China.
Qiaorui YangDepartment of Gynecology, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Mengfan YangGraduate School, Chengdu Chinese Medical University, Chengdu, China.
Riping YinNephrology and Endocrinology Department, Pinghu Hospital of Traditional Chinese Medicine, Pinghu, China.
Dongxue ZhaoHealth Institute, Harbin Institute of Physical Education, Harbin, China.
Junfen FanNephrology Department, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Hongzhen MaNephrology Department, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Yiwei ShenOrthopedics Department, Ningbo Hospital of Traditional Chinese Medicine (Ningbo Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Chinese Medicine), Ningbo, China.
Hong XiaNephrology Department, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Wenze JiangDepartment of Nephrology, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Keda LuDepartment of Nephrology, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

Funding

National Science Foundation of China 82104756Science Foundation of Zhejiang province LQ22H270002
6 · The paper itself

Abstract

In hemodialysis patients, blood pressure variability (BPV) is associated with cardiovascular events and all-cause mortality. However, previous research has predominantly concentrated on the predialysis BPV. In contrast, intradialytic BPV, reflecting the cardiovascular regulatory function during the process of rapid clearance of volume overload, holds greater relevance to the prognosis of patients. In this study, a latent category trajectory model was used to identify the patterns of intradialytic BPV and analyze the association between intradialytic BPV and the cardio-cerebrovascular events and other clinical outcomes. We found the variation of intradialytic systolic blood pressure (SBP) was associated with the risk of cardio-cerebrovascular events in hemodialysis patients. Patients in "SBP Class 4" and "SBP Class 3" subgroups were associated with the occurrence of cardio-cerebrovascular events and the number of cardio-cerebrovascular event hospitalizations during the follow-up period. This indicates that the variation pattern of intradialytic SBP results from the comprehensive action of various BP regulatory mechanisms in the body, which can reflect the level of cardiovascular regulatory function in hemodialysis patients and serve as a predictor of recent adverse cardio-cerebrovascular events.

Indexed as

Blood PressureCardiovascular DiseasesCerebrovascular DisordersHypertensionKidney Failure, ChronicRenal DialysisAgedBlood Pressure DeterminationFemaleHumansMaleMiddle AgedPrognosisRisk Factorsblood pressure variabilitycardio‐cerebrovascular eventshemodialysislatent category trajectory model

Identifiers

PMID39654485
PMCPMC11774084

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.