Evidence map›Paper›PMID 39653854›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

PRO-QOL after gross total resection of spinal ependymoma: a retrospective study based on 3-year follow-up observations in a single center.

Dingbang Chen, Tianxiang Shao, Haocheng Zhu, Xin Gao, Quan Huang, Xinghai Yang, Qi Jia, Jianru Xiao

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Preoperative risk stratification for long-term neurological status in spinal ependymoma: an MRI-centered nomogram.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dingbang Chen *The Center of Spinal Oncology, Department of Orthopedics, Changzheng Hospital, Naval Military Medical University, Shanghai, China.
Tianxiang Shao *The Center of Spinal Oncology, Department of Orthopedics, Changzheng Hospital, Naval Military Medical University, Shanghai, China.
Haocheng Zhu *The Center of Spinal Oncology, Department of Orthopedics, Changzheng Hospital, Naval Military Medical University, Shanghai, China.
Xin GaoThe Center of Spinal Oncology, Department of Orthopedics, Changzheng Hospital, Naval Military Medical University, Shanghai, China.
Quan HuangThe Center of Spinal Oncology, Department of Orthopedics, Changzheng Hospital, Naval Military Medical University, Shanghai, China.
Xinghai YangThe Center of Spinal Oncology, Department of Orthopedics, Changzheng Hospital, Naval Military Medical University, Shanghai, China. cnspineyang@163.com.
Qi JiaThe Center of Spinal Oncology, Department of Orthopedics, Changzheng Hospital, Naval Military Medical University, Shanghai, China. doctorjiaqi@126.com.
Jianru XiaoThe Center of Spinal Oncology, Department of Orthopedics, Changzheng Hospital, Naval Military Medical University, Shanghai, China. czjianruxiao83@163.com.

Funding

Construction Project of Orthopedic Clinical Medical Research Center 21MC1930100Construction Project of Shanghai Municipal Health Commission's Priority Research Center 2022ZZ01013Shanghai Rising-Star Program 23QA1411700Special Program for Clinical Research in the Health Industry of Shanghai Municipal Health Commission 20224Y0073
6 · The paper itself

Abstract

backgroundAlthough many studies have reported clinical outcomes of spinal ependymoma (SE) patients after gross total resection (GTR), the data about the patient reported outcomes of the quality of life (PRO-QOL) was limited. PURPOSE: This study investigated the recovery process of PRO-QOL and explored the possibility of predicting the recovery of postoperative QOL by preoperative clinical indicators.

methodsA retrospective analysis was performed in 71 SE patients who underwent GTR in our center from 2016 to 2022. The PRO-QOL data were collected by questionnaire, which included the EuroQol 5-Dimensions 5-Levels (EQ-5D-5 L) scale and visual pain analogue score (VAS). Factors affecting postoperative PRO-QOL deterioration was assessed by the univariate and multivariate analyses.

results71 SE patients who undergone GTR were included and followed by mean of 36 months (range 27-58). The overall PRO-QOL recovered to a stable level 6 months after surgery, but the ability of self-care, as one of the dimensions of QOL, continued to improve up to one year after surgery. 21 (29.6%) patients reported that their QOL became worse at one year after surgery. The result of statistical analysis suggested that preoperative Modified McCormick Scale (MMS), the number of segments involved by the tumor and preoperative VAS score were identified as main preoperative variables for predicting QOL deterioration.

conclusionFrom the perspective of PRO-QOL, neurological rehabilitation should be continued for at least 6-12 months after GTR to the SE patients. For the preoperative patients with severe neurological damage, long-level intraspinal tumor and low VAS score, more cautious surgical considerations, more perioperative attention and earlier neurological intervention are necessary.

Indexed as

EpendymomaPatient Reported Outcome MeasuresQuality of LifeSpinal Cord NeoplasmsAdolescentAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedNeurosurgical ProceduresRetrospective StudiesTreatment OutcomeYoung AdultGross total resectionPatient reported outcomeQuality of lifeSpinal ependymoma

Identifiers

PMID39653854

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