Evidence map›Paper›PMID 39653050›Full record

ReviewThe Lancet. Microbe2025

Socioeconomic status and the risk for colonisation or infection with priority bacterial pathogens: a global evidence map.

Sarah Blackmon, Esther E Avendano, Nanguneri Nirmala, Courtney W Chan, Rebecca A Morin, Sweta Balaji, Lily McNulty, Samson Alemu Argaw, Shira Doron, Maya L Nadimpalli

Abstract readReview
In one paragraph

Review in The Lancet. Microbe, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Methicillin-resistant Staphylococcus aureus.Nature reviews. Disease primers · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Temporal trends and patterns in neonatal sepsis mortality across 194 countries, 2000-2021, with projections up to 2050.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  13. ASP-COMPLEX: redefining antimicrobial stewardship to improve outcomes in high-risk patients with severe infections.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  14. Article
  15. The threat of multidrug-resistant microorganisms: active surveillance of key antimicrobial resistant pathogens in 2025 - a report from the INVIFAR network.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Sarah BlackmonDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Esther E AvendanoWCG Clinical, Princeton, NJ, USA.
Nanguneri NirmalaInstitute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA.
Courtney W ChanT H Chan School of Medicine, University of Massachusetts, Worcester, MA, USA.
Rebecca A MorinHirsh Health Sciences Library, Tufts University, Boston, MA, USA.
Sweta BalajiDepartment of Quantitative Theory and Methods, Emory University, Atlanta, GA, USA.
Lily McNultyHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Samson Alemu ArgawHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Shira DoronDivision of Geographic Medicine and Infectious Disease, Department of Medicine, Tufts Medical Center, Boston, MA, USA; Stuart B Levy Center for Integrated Management of Antimicrobial Resistance, Tufts University, Boston, MA, USA.
Maya L NadimpalliGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA; Stuart B Levy Center for Integrated Management of Antimicrobial Resistance, Tufts University, Boston, MA, USA. Electronic address: maya.l.nadimpalli@emory.edu.

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

Low socioeconomic status likely exacerbates risks for bacterial infections; however, global evidence for this relationship has not been synthesised. We systematically reviewed the existing literature for studies detailing the socioeconomic status of participants and their risk for colonisation or community-acquired infection with priority bacterial pathogens that are increasingly becoming antibiotic resistant. 50 studies from 14 countries reported outcomes by the participants' educational attainment, access to health care, income level, residential crowding status, socioeconomic status deprivation score, community setting, or access to clean water, sanitation, and hygiene. Low educational attainment, lower than average income levels, inadequate access to health care, presence of residential crowding, and high socioeconomic status deprivation scores were generally associated with elevated risks of colonisation or infection. Limited research has been conducted on these outcomes in low-income and middle-income countries, and findings regarding the effects of community settings (eg, urban vs rural) on these outcomes have been conflicting. Only a proportion of studies focused on pathogen colonisation and infection yielded data stratified by the socioeconomic status of participants. Stratified data should be included in future research to enhance understanding of the complex relationship between socioeconomic status and health, particularly in low-income and middle-income countries.

Indexed as

BacteriaBacterial InfectionsCommunity-Acquired InfectionsSocial ClassGlobal HealthHumansRisk FactorsSocioeconomic Factors

Identifiers

PMID39653050
PMCPMC12103885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.