Evidence map›Paper›PMID 39652967›Full record

ArticleDermatology practical & conceptual2024

Dermoscopy of Lichen Planus Pigmentosus and Histopathological Correlation: A Case Series.

Amal Chamli, Malek Mrad, Houda Hammami, Imen Helal, Anissa Zaouak, Samy Fenniche

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Article in Dermatology practical & conceptual, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Amal ChamliDermatology Department, Habib Thameur Hospital, Tunis, Tunisia.
Malek MradDermatology Department, Habib Thameur Hospital, Tunis, Tunisia.
Houda HammamiDermatology Department, Habib Thameur Hospital, Tunis, Tunisia.
Imen HelalUniversity of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.
Anissa ZaouakDermatology Department, Habib Thameur Hospital, Tunis, Tunisia.
Samy FennicheDermatology Department, Habib Thameur Hospital, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLichen planus pigmentosus (LPP) is an acquired pigmentary disorder affecting the dark-skinned population. There is a wide range of differentials, with substantial clinicopathological overlap. Dermoscopy may contribute to the better characterization of this dermatosis.

objectiveThis study aimed to describe dermoscopic features of LPP with a histopathological correlation.

methodsLPP lesions of 23 patients were studied using a polarized dermoscopy, followed by histological evaluation.

resultsThe most common dermoscopic finding was dots and/or globules (n=23) in different patterns: speckled (n=4), dotted (n=2), reticular (n=4), diffuse (n=9), hem-like (n=1), and circular (n=2). Other patterns were exaggerated pseudo-reticular pattern (n=12), sparing of follicular openings (n=23), targetoid appearance (n=3), blue-white veil (n=5), rosettes (n=5), erythema (n=4), and telangiectasia (n=7). Histological findings included pigment incontinence (n=23), the severity being mild (n=8) and severe (n=15). We found a statistically significant association between the intensity of pigmentary incontinence on the histological examination and the presence of blotches in dermoscopy (P=0.046) and between blue-white veil and rosettes in flexural areas (P=0.01). Also, a statistical relationship was found between severe pigment density (reticulated and diffused patterns) and short disease duration (P=0.016).

conclusionWe describe LPP dermoscopic changes according to disease progression. We found that blotches are indicative of long-duration disease and could be specific dermoscopic features of LPP. We demonstrate that a blue-white veil associated with rosettes could be pathognomonic features of LPP inversus.

Identifiers

PMID39652967
PMCPMC11620012

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