Evidence map›Paper›PMID 39652927›Full record

ReviewDermatology practical & conceptual2024

Clinical and Dermoscopic Characteristics of Cutaneous Chondroid Syringoma: A Systematic Review.

Antonio Di Guardo, Charalampos G Balampanos, Luca Gargano, Domenico Giordano, Alessandro Capalbo, Flavia Persechino, Severino Persechino

Abstract readReview
In one paragraph

Review in Dermatology practical & conceptual, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. S1 guideline sweat gland carcinoma.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Antonio Di GuardoDepartment of Dermatology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Charalampos G BalampanosDepartment of Dermatology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Luca GarganoDepartment of Dermatology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Domenico GiordanoDepartment of Dermatology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Alessandro CapalboDepartment of Dermatology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Flavia PersechinoDepartment of Dermatology, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Severino PersechinoDepartment of Dermatology, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCutaneous chondroid syringoma (CS) is a rare benign mixed skin tumor originating from sweat glands. Despite its rarity, accurate diagnosis and management are crucial due to its potential for malignant transformation.

objectiveThis study aimed to provide comprehensive insights into the main features of cutaneous CS, encompassing its epidemiology, clinical presentation, and particularly, dermoscopic findings.

methodsA systematic review was conducted to identify relevant literature on CS up to November 2023. Data extraction included clinical and histopathological characteristics from case reports and small case series.

resultsThe systematic review identified 347 unique CS cases, predominantly benign. Clinical features included a predilection for the head and neck region, with variations in morphology observed. Dermoscopic patterns, although limited, revealed recurrent features aiding diagnosis. Malignant CS cases constituted a notable subset, exhibiting distinct clinical and histopathological features.

conclusionCutaneous chondroid syringoma presents with characteristic clinical and histopathological features, necessitating comprehensive diagnostic approaches. Dermoscopy emerges as a valuable tool, although further research is needed to establish definitive patterns. Treatment primarily involves wide local excision, with collaboration among clinicians essential for optimal management. Future studies are warranted to address existing knowledge gaps and enhance understanding of this rare skin neoplasm.

Identifiers

PMID39652927
PMCPMC11620009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.