Evidence map›Paper›PMID 39652765›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

AI-boosted and motion-corrected, wireless near-infrared sensing system for continuously monitoring laryngeal muscles.

Yihan Liu, Arjun Putcha, Gavin Lyda, Nanqi Peng, Salil Pai, Tien Nguyen, Sicheng Xing, Shang Peng, Yiyang Fan, Yizhang Wu and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yihan LiuDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0003-3671-9191
Arjun PutchaDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.
Gavin LydaDepartment of Physics and Astronomy, University of North Carolina, Chapel Hill, NC 27599.
Nanqi PengJoint Department of Biomedical Engineering, University of North Carolina/North Carolina State University, Chapel Hill, NC 27599.
Salil PaiJoint Department of Biomedical Engineering, University of North Carolina/North Carolina State University, Chapel Hill, NC 27599.
Tien NguyenDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.
Sicheng XingJoint Department of Biomedical Engineering, University of North Carolina/North Carolina State University, Chapel Hill, NC 27599.
Shang PengDepartment of Computer Science, University of North Carolina, Chapel Hill, NC 27599.
Yiyang FanDepartment of Biostatistics, University of North Carolina, Chapel Hill, NC 27599.
Yizhang WuDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0001-6244-8458
Wanrong XieDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.ORCID 0009-0001-5872-1228
Wubin BaiDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0003-2872-5559

Funding

Wearable, Wireless Deep-tissue Sensing Patch for Continuous Monitoring of Recovery from Microsurgical Tissue TransferR01EB034332 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wubin Bai · 2023 to 2026
$1.3M
HHS | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) 1R01EB034332-01NIBIB NIH HHS R01 EB034332NSF (NSF) ECCS-2139659
6 · The paper itself

Abstract

Neuromuscular diseases pose significant health and economic challenges, necessitating innovative monitoring technologies for personalizable treatment. Existing devices detect muscular motions either indirectly from mechanoacoustic signatures on skin surface or via ultrasound waves that demand specialized skin adhesion. Here, we report a wireless wearable system, Laryngeal Health Monitor (LaHMo), designed to be conformally placed on the neck for continuously measuring movements of underlying muscles. The system uses near-infrared (NIR) light that features deep-tissue penetration and strong interaction with myoglobin to capture muscular locomotion. The incorporated inertial measurement unit sensor further decouples the superposition of signals from NIR recordings. Integrating a multimodal AI-boosted algorithm based on recurrent neural network, the system accurately classifies activities of physiological events. An adaptive model enables fast individualization without enormous data sources from the target user, facilitating its broad applicability. Long-term tests and simulations suggest the potential efficacy of the LaHMo platform for real-world applications, such as monitoring disease progression in neuromuscular disorders, evaluating treatment efficacy, and providing biofeedback for rehabilitation exercises. The LaHMo platform may serve as a general noninvasive, user-friendly solution for assessing neuromuscular function beyond the anterior neck, potentially improving diagnostics and treatment of various neuromuscular disorders.

Indexed as

Laryngeal MusclesWireless TechnologyAlgorithmsHumansInfrared RaysMonitoring, PhysiologicNeural Networks, ComputerSpectroscopy, Near-InfraredWearable Electronic DevicesAIhardware AIneuromuscular diseaseswearable near-infrared spectroscopy

Identifiers

PMID39652765
PMCPMC11665861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.