Evidence map›Paper›PMID 39652432›Full record

ArticleCritical care explorations2024

What Clinicians Think About When They Think About Sepsis: Results From a Survey Across the University of Maryland Medical System.

Jerry M Yang, Samuel A Tisherman, Surbhi Leekha, Angela Smedley, Blaine Kenaa, Samantha King, Connie Wu, David J Kim, Dorsey Dowling, Jonathan D Baghdadi

Abstract read
In one paragraph

Article in Critical care explorations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jerry M YangDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD.
Samuel A TishermanDepartment of Surgery and the Program in Trauma, University of Maryland School of Medicine, Baltimore, MD.
Surbhi LeekhaDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD.
Angela SmedleyDepartment of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD.
Blaine KenaaDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD.
Samantha KingDepartment of Emergency Medicine, School of Public and Population Health, University of Texas Medical Branch,Galveston, TX.
Connie WuDepartment of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD.
David J KimKaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA.
Dorsey DowlingUniversity of Maryland Medical System, Baltimore, MD.
Jonathan D BaghdadiDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-2442-0654

Funding

Optimizing Implementation of Multiplex Molecular Panel Testing to Reduce Diagnostic ErrorK08HS028854 · AHRQ · UNIVERSITY OF MARYLAND BALTIMORE · PI BAGHDADI, JONATHAN · 2022 to 2025
$594k
AHRQ HHS K08 HS028854
6 · The paper itself

Abstract

importanceSepsis, a leading cause of death in the hospital, is a heterogeneous syndrome without a defined or specific set of symptoms.

objectivesWe conducted a survey of clinicians in practice to understand which clinical findings they tend to associate with sepsis. DESIGN, SETTING, AND

participantsA survey was distributed to physicians and advanced practice providers across a multihospital health system during April 2022 and May 2022 querying likelihood of suspecting sepsis and initiating sepsis care in response to various normal and abnormal clinical findings. ANALYSIS: Strength of association between clinical findings and suspicion of sepsis were based on median and interquartile range of complete responses. Comparisons between individual questions were performed using Wilcoxon rank-sum testing.

resultsAmong 179 clinicians who opened the survey, 68 (38%) completed all questions, including 53 (78%) attending physicians representing six different hospitals. Twenty-nine respondents (43%) worked primarily in the ICU, and 16 (24%) worked in the emergency department. The clinical findings most strongly associated with suspicion of sepsis were hypotension, tachypnea, coagulopathy, leukocytosis, respiratory distress, and fever. The abnormal clinical findings least likely to prompt suspicion for sepsis were elevated bilirubin, elevated troponin, and abdominal examination suggesting ileus. On average, respondents were more likely to suspect sepsis with high temperature than with low temperature (p = 0.008) and with high WBC count than with low WBC count (p = 0.003).

conclusionsClinicians in practice tend to associate the diagnosis of sepsis with signs of severe illness, such as hypotension or respiratory distress, and systemic inflammation, such as fever and leukocytosis. Except for coagulopathy, nonspecific laboratory indicators of organ dysfunction have less influence on decision-making.

Indexed as

SepsisHumansIntensive Care UnitsMarylandPhysiciansSurveys and Questionnaires

Identifiers

PMID39652432
PMCPMC11630952

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.