Evidence map›Paper›PMID 39651754›Full record

ArticleJournal of addiction medicine

Heterogeneity in Prescription Opioid Misuse Motives by Age in Adolescents and Young Adults in the United States.

Ty S Schepis, Jason A Ford, Philip T Veliz, Brady T West, Sean Esteban McCabe

Abstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ty S SchepisDepartment of Psychology, Texas State University, San Marcos, TX (TSS); Center for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, MI (TSS, JAF, PTV, BTW, SEM); Department of Sociology, University of Central Florida, Orlando, FL (JAF); Institute for Social Research, University of Michigan, Ann Arbor, MI (PTV, BTW, SEM); Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI (PTV, SEM); and Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI (PTV, BTW, SEM).ORCID 0000-0001-7887-5286
Jason A Ford
Philip T Veliz
Brady T West
Sean Esteban McCabe

Funding

Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
Prescription Drug Misuse Characteristics in Adolescents and Young Adults: Influence of School EnrollmentR01DA043691 · NIDA · TEXAS STATE UNIVERSITY · PI TY Stephen SCHEPIS · 2017 to 2026
$1.8M
NIDA NIH HHS R01 DA031160NIDA NIH HHS R01 DA043691
6 · The paper itself

Abstract

objectiveAdolescent (12-17 years) and young adult (18-25 years) prescription opioid misuse (POM) is linked to poor health outcomes. We investigated how POM motives vary across these ages and the potential links between motives and other substance use, mental health, and sociodemographic characteristics to help guide screening and prevention.

methodsPooled 2015-2019 US National Survey on Drug Use and Health data were used, with 137,858 participants. Cross-tabulations estimated prevalence of individual motives and motive category by age. Mutually exclusive motive categories were no past-year POM, pain relief only, pain/sleep/relax (ie, some combination of only these motives), and any non-self-treatment motives (eg, get high, experiment). Logistic regression models evaluated links between motive category and sociodemographic, mental health, and substance use (eg, alcohol, cannabis, nicotine, other prescription misuse) outcomes by age group, versus reference groups of no past-year POM or pain relief only.

resultsPain relief was the most common POM motive (estimated at >50% at all ages), but POM for non-self-treatment motives was the most common category after 14 years. POM for non-self-treatment motives had the highest adjusted odds ratios (aORs) of all substance use and mental health characteristics (eg, past-year substance use disorder aORs of 6.11 in adolescents [95% confidence interval (CI), 4.23-8.85] and 4.81 [95% CI, 4.01-5.77] in young adults, versus the pain relief only reference).

conclusionsPOM for any non-self-treatment motives is linked to the highest prevalence of other substance use and mental health concerns, whereas POM for pain relief also signals a need for substance use and mental health screening.

Indexed as

Analgesics, OpioidMotivationOpioid-Related DisordersPrescription Drug MisuseAdolescentAdultAge FactorsChildFemaleHealth SurveysHumansMaleUnited StatesYoung AdultAnalgesics, Opioidadolescentsmotiveopioidprescription drug misuseyoung adults

Identifiers

PMID39651754
PMCPMC12146424

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.