ArticleNeurogastroenterology and motility2026
Smooth Muscle Mechanosensitivity Generates and Maintains Pressure Gradients Across the Intestine.
Article in Neurogastroenterology and motility, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Quantitative analysis of ureteral peristalsis in healthy women using transvaginal ultrasound combined with peristaltic analysis technology: a feasibility study.Frontiers in bioengineering and biotechnology · 2026Article
- Smooth Muscle Mechanosensitivity Generates and Maintains Pressure Gradients Across the Intestine.Neurogastroenterology and motility · 2026Article
- Feasibility and tolerability of electrical muscle stimulation during rehabilitation in older adults with osteoporotic vertebral fractures.Osteoporosis and sarcopenia · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundThe gut, the ureter, or the Fallopian tube all transport biological fluids by generating trains of propagating smooth muscle constrictions collectively known as peristalsis. These tubes connect body compartments at different pressures. We extend here Poiseuille's experiments on liquid flow in inert tubes to an active, mechanosensitive tube: the intestine.
methodsWe use as a miniature myogenic peristaltic pump model, the fetal chicken gut, and measured the flow and contractile wave propagation as a function of the initially applied pressures and pressure gradients. We dissect the molecular pathways of smooth muscle mechanosensitivity by measuring the force generated by gut rings in different pharmacological conditions.
resultsWe demonstrate that smooth muscle contractions in response to stretch or pressure is mediated by L-type Ca
conclusionsWe provide fundamental mechanical and hydrodynamic insight into the myogenic mechanisms of transport in the gastrointestinal tract. We scale up our results to other human peristaltic organs and discuss their implications for pathophysiology of intestinal obstruction, vesicoureteral reflux and endometriosis.
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