Evidence map›Paper›PMID 39651454›Full record

ArticleEpilepsy & behavior reports2024

A case of acute functional hemispherotomy in a young woman with hemimegalencephaly and super-refractory status epilepticus.

Kjell Heuser, Louis Romundstad, Jugoslav Ivanovic, Arild Egge, Erik Sætre, Kristin Alfstad, Line Sveberg, Line Bedos Ulvin, Erik Taubøll

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In one paragraph

Article in Epilepsy & behavior reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kjell HeuserDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Louis RomundstadDepartment of Anesthesia and Intensive Care Medicine, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.
Jugoslav IvanovicDepartment of Neurosurgery, Division of Stereotactic and Functional Neurosurgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Arild EggeDepartment of Neurosurgery, Division of Stereotactic and Functional Neurosurgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Erik SætreNational Center for Epilepsy, Member of the ERN EpiCARE, Oslo University Hospital, Oslo, Norway.
Kristin AlfstadNational Center for Epilepsy, Member of the ERN EpiCARE, Oslo University Hospital, Oslo, Norway.
Line SvebergDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Line Bedos UlvinSection for Clinical Neurophysiology, Department of Neurology, Oslo University Hospital, Oslo, Norway.
Erik TaubøllDepartment of Neurology, Oslo University Hospital, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Status epilepticus (SE) is a critical medical emergency that demands immediate and effective intervention. We report a unique case involving a 21-year-old woman with left hemimegalencephaly who was hospitalized for super-refractory status epilepticus (SRSE) that persisted for 8 weeks. Despite extensive treatment efforts including multiple anti-seizure medications, anesthetics, high-dose methylprednisolone, anakinra, magnesium infusion, and a ketogenic diet, her condition remained unchanged. Ultimately, a left functional hemispherotomy was performed, informed by MRI findings and EEG results showing predominantly left-sided epileptic activity. This decision was made collaboratively when all other therapeutic options had been exhausted. Postoperatively, the patient recovered with manageable neurological deficits and a satisfactory quality of life. To our knowledge, this is the first reported case of acute functional hemispherotomy in an adult with hemimegalencephaly and SRSE.

Indexed as

EpilepsyEpilepsy surgeryFunctional hemispherotomyHemimegalencephalyStatus epilepticusSuper-refractory status epilepticus

Identifiers

PMID39651454
PMCPMC11625172

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.