Evidence map›Paper›PMID 39650961›Full record

ArticleCureus2024

Recurrent Corneal Erosion Induced by 1% 5-Fluorouracil Solution.

Hayato Tanaka, Hitoshi Tabuchi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hayato TanakaOphthalmology, Tsukazaki Hospital, Himeji, JPN.
Hitoshi TabuchiOphthalmology, Hiroshima University, Hiroshima, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytotoxic anticancer drug solution eye drops can hinder the cell division of corneal basal cell division and corneal limbal epithelial stem cell migration. We discuss a case involving recurrent corneal epithelial erosions induced by 1% 5-fluorouracil (5-FU) solution eye drops. A 68-year-old male with conjunctival papilloma on his left eye underwent recurrences three times and additional tumor excision. He was prescribed 1% 5-FU solution eye drops two times a day without drug holidays and experienced recurrent corneal epithelial erosion. This report highlights the necessity of drug holidays for patients receiving cytotoxic anticancer drug solution eye drops.

Indexed as

5-fluorouracilchemo-holidaysconjunctival papillomacorneal epithelial erosioncytotoxic anticancer drugs

Identifiers

PMID39650961
PMCPMC11624916

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.