Evidence map›Paper›PMID 39650912›Full record

ReviewCureus2024

A Review of Photon-Counting Computed Tomography (PCCT) in the Diagnosis of Cardiovascular Diseases.

Astha Sharma, Maria Gabriela Cerdas, Setareh Reza-Soltani, Vikash Rustagi, Manojna Guntipalli, Diana Stefanie Rojas Torres, Mrinal Bhandari, Shreya Kandel, Dharma Teja Rayaprolu, Mohammed Hussain

Registry-linked trialAbstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07020039 (Comparing Photon Counting Computed Tomography With Invasive Coronary Angiography and Intravascular Ultrasound in Detecting Cardiac Allograft Vasculopathy), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07020039 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Comparing Photon Counting Computed Tomography With Invasive Coronary Angiography and Intravascular Ultrasound in Detecting Cardiac Allograft Vasculopathy

Typeobservational_patient_registrySponsorSahlgrenska University HospitalRan2025 to 2027Enrolled100ConditionsCardiac Allograft Vasculopathy
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Astha SharmaMedicine, University Hospital Birmingham NHS Foundation Trust, Birmingham, GBR.
Maria Gabriela CerdasMedicine, University of Medical Sciences (UCIMED), San Jose, CRI.
Setareh Reza-SoltaniRadiology, Advanced Diagnostic & Interventional Radiology Center (ADIR) Tehran University of Medical Sciences, Tehran, IRN.
Vikash RustagiRadiology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale Galeazzi, Milano, ITA.
Manojna GuntipalliMedicine, Gandhi Institute of Technology and Management (GITAM) Institute of Medical Sciences and Research, Visakhapatnam, IND.
Diana Stefanie Rojas TorresCadiology, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, USA.
Mrinal BhandariCardiology, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, USA.
Shreya KandelMedicine, University Hospital Southampton NHS Foundation Trust, Southhampton, GBR.
Dharma Teja RayaproluInternal Medicine, Mamata Medical College, Khammam, IND.
Mohammed HussainRespiratory Medicine, Royal Stoke University Hospital, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photon-counting computed tomography (PCCT) is an innovative mechanism used for imaging and provides higher spatial resolution and contrast sensitivity in comparison with the orthodox energy-integrating detectors (EIDs). Unlike EID-based CT systems, which indirectly convert X-ray photons to electrical signals, PCCT directly counts and quantifies each photon's energy, enhancing image quality and material separation. With all of these features, PCCT is especially useful for cardiovascular imaging, where it is essential to precisely observe cardiac tissues, vascular structures, and coronary arteries. Around the globe, cardiovascular diseases (CVDs) continue to be the primary cause of morbidity and death, and early, precise diagnosis is essential for effective management. This review examines the role of PCCT in diagnosing CVDs, highlighting its enhanced capabilities in improving the precision in diagnosis as well as patient outcomes compared to conventional CT methods. While current evidence supports PCCT's advantages, further research is necessary to validate these findings and facilitate its broader clinical adoption.

Indexed as

cardiovascular imagingcontrast sensitivitydiagnosisenergy-integrating detectorsphoton-counting computed tomographyspatial resolution

Identifiers

PMID39650912
PMCPMC11622532

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.