ArticleCureus2024
Candidemia Surveillance and Impact on Non-neutropenic Critically Ill Patients.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCandidemia is a common pathogen in critically ill patients and has a significant negative impact on morbidity and mortality. Risk factors linked with candidemia are reported in the literature. We evaluated the risk factors associated with candidemia in critically ill patients on mortality rates, including the impact of delayed or inadequate antifungal therapy (IAAT).
methodsThis retrospective study evaluated non-neutropenic critically ill adult patients with candidemia for six consecutive years. Antifungal therapy was evaluated for the following: the correct dose based on the
resultsIn the 91 critically ill patients evaluated with documented candidemia, the mean age was 57±16 years, the mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score was 25±9, and the overall mortality rate was 38%. Patients with the following risk factors for candidemia had an increased mortality: use of mechanical ventilation (35 (100%), p<0.001), vasopressor therapy (28 (80%), p<0.001), end-stage renal disease (ESRD) (11 (31%), p<0.001), and ≥ 2 organ failure (23 (65%), p=0.002). Mortality was also more likely in patients who received IAAT: 16 (64%) IAAT vs. 19 (29%) AAT, p=0.001.
conclusionsIn critically ill patients with risk factors associated with candidemia, AAT is important when candidemia is suspected. This study found that
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