ArticleCureus2024
An Exploratory Study on the Efficacy of a New Heat and Moisture Exchanger (Provox® LifeTM) for Laryngectomized Patients.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Cost-effectiveness analysis of third-generation heat and moisture exchangers in patients who underwent laryngectomy in Japan.Cost effectiveness and resource allocation : C/E · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAfter a total laryngectomy, patients lose various physiological functions of the upper airway. To address these issues, an artificial nose (heat and moisture exchanger (HME)) has been developed. However, the current HMEs do not provide sufficient physiological upper airway function. We prospectively investigated the efficacy of a new type of HME and compared it with that of the current type.
methodsThis was a pre- and post-comparative study comparing the efficacy of the current HME and the new HME using a questionnaire (physiological upper airway function, skin complications, and adherence, especially for nocturnal HME). Patients who underwent laryngectomy were asked to use the new type of HME for six weeks and to complete questionnaires three days before and six weeks after starting the use of the new HME. The values for each question were statistically compared using paired
resultsA significant decrease in the number of coughs per day was observed (before use: 6.89, after use: 3.16; p = 0.049). The degree of dyspnea significantly improved (before use: 7.77 cm, after use: 9.28 cm; p = 0.013). The number of days of nocturnal HME use improved significantly from 0 days to 33.32/42 days after the use of the new HME (p <0.0001).
conclusionTo the best of our knowledge, for the first time in Japan, we showed that the new HME can improve respiratory symptoms, such as the number of coughs per day, degree of breathlessness, and nocturnal HME use.
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